Anti-RFC2 抗体 (ab3615)
Key features and details
- Goat polyclonal to RFC2
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-RFC2 antibody
RFC2 一次抗体 製品一覧 -
製品の詳細
Goat polyclonal to RFC2 -
由来種
Goat -
特異性
We have data to indicate that this antibody may not cross react with Mouse. However, this has not been conclusively tested and expression levels may vary in certain cell lines/tissues. -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human -
免疫原
Synthetic peptide (Human) - which represented a portion of human Replication Factor C 2 40 kDa subunit encoded within exon 1.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
pH: 7
Preservative: 0.1% Sodium azide
Constituents: 0.021% PBS, 1.764% Sodium citrate, 1.815% Tris -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab3615の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
1/500 - 1/5000. Detects a band of approximately 40 kDa (predicted molecular weight: 40 kDa).
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| 特記事項 |
|---|
|
WB
1/500 - 1/5000. Detects a band of approximately 40 kDa (predicted molecular weight: 40 kDa). |
ターゲット情報
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機能
The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. This subunit binds ATP. -
関連疾患
Note=RFC2 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region. -
配列類似性
Belongs to the activator 1 small subunits family. -
細胞内局在
Nucleus. - Information by UniProt
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参照データベース
- Entrez Gene: 5982 Human
- Omim: 600404 Human
- SwissProt: P35250 Human
- Unigene: 647062 Human
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別名
- A1 40 kDa subunit antibody
- A1 antibody
- Activator 1 40 kDa subunit antibody
see all
画像
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Western blot - Anti-RFC2 antibody (ab3615)
Sample: 50
µ g Hela cell nuclear extractanti-RFC 2 (exon 1) (ab3615) used at 1:1000 dilution
Sample: 50
µg Hela cell nuclear extract anti-RFC 2 (exon 1) (ab3615) used at 1:1000 dilution
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (2)
ab3615 は 2 報の論文で使用されています。
- Kawasoe Y et al. MutSa maintains the mismatch repair capability by inhibiting PCNA unloading. Elife 5:N/A (2016). PubMed: 27402201
- Nicolas A et al. Identification of rep-associated factors in herpes simplex virus type 1-induced adeno-associated virus type 2 replication compartments. J Virol 84:8871-87 (2010). IF . PubMed: 20573815