Anti-RFC2 抗体 (ab3615)
Key features and details
- Goat polyclonal to RFC2
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-RFC2 antibody
RFC2 一次抗体 製品一覧 -
製品の詳細
Goat polyclonal to RFC2 -
由来種
Goat -
特異性
We have data to indicate that this antibody may not cross react with Mouse. However, this has not been conclusively tested and expression levels may vary in certain cell lines/tissues. -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human -
免疫原
Synthetic peptide (Human) - which represented a portion of human Replication Factor C 2 40 kDa subunit encoded within exon 1.
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特記事項
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
pH: 7
Preservative: 0.1% Sodium azide
Constituents: 0.021% PBS, 1.764% Sodium citrate, 1.815% Tris -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
Our Abpromise guarantee covers the use of ab3615 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB | 1/500 - 1/5000. Detects a band of approximately 40 kDa (predicted molecular weight: 40 kDa). |
ターゲット情報
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機能
The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. This subunit binds ATP. -
関連疾患
Note=RFC2 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region. -
配列類似性
Belongs to the activator 1 small subunits family. -
細胞内局在
Nucleus. - Information by UniProt
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参照データベース
- Entrez Gene: 5982 Human
- Omim: 600404 Human
- SwissProt: P35250 Human
- Unigene: 647062 Human
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別名
- A1 40 kDa subunit antibody
- A1 antibody
- Activator 1 40 kDa subunit antibody
see all
画像
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Western blot - Anti-RFC2 antibody (ab3615)
Sample: 50
µ g Hela cell nuclear extractanti-RFC 2 (exon 1) (ab3615) used at 1:1000 dilution
Sample: 50
µg Hela cell nuclear extract anti-RFC 2 (exon 1) (ab3615) used at 1:1000 dilution
プロトコール
参考文献 (2)
ab3615 は 2 報の論文で使用されています。
- Kawasoe Y et al. MutSa maintains the mismatch repair capability by inhibiting PCNA unloading. Elife 5:N/A (2016). PubMed: 27402201
- Nicolas A et al. Identification of rep-associated factors in herpes simplex virus type 1-induced adeno-associated virus type 2 replication compartments. J Virol 84:8871-87 (2010). IF . PubMed: 20573815
