Key features and details
- Goat polyclonal to RFC2
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
RFC2 一次抗体 製品一覧
製品の詳細Goat polyclonal to RFC2
特異性We have data to indicate that this antibody may not cross react with Mouse. However, this has not been conclusively tested and expression levels may vary in certain cell lines/tissues.
アプリケーション適用あり: WBmore details
Synthetic peptide (Human) - which represented a portion of human Replication Factor C 2 40 kDa subunit encoded within exon 1.
保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
バッファーPreservative: 0.1% Sodium azide
Constituents: 0.021% PBS, 1.764% Sodium citrate, 1.815% Tris
Concentration information loading...
精製度Immunogen affinity purified
Our Abpromise guarantee covers the use of ab3615 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/5000. Detects a band of approximately 40 kDa (predicted molecular weight: 40 kDa).|
機能The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. This subunit binds ATP.
関連疾患Note=RFC2 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region.
配列類似性Belongs to the activator 1 small subunits family.
- Information by UniProt
- A1 40 kDa subunit antibody
- A1 antibody
- Activator 1 40 kDa subunit antibody
ab3615 は 2 報の論文で使用されています。
- Kawasoe Y et al. MutSa maintains the mismatch repair capability by inhibiting PCNA unloading. Elife 5:N/A (2016). PubMed: 27402201
- Nicolas A et al. Identification of rep-associated factors in herpes simplex virus type 1-induced adeno-associated virus type 2 replication compartments. J Virol 84:8871-87 (2010). IF . PubMed: 20573815