Key features and details
- Rabbit polyclonal to Retinoic Acid Receptor beta
- Suitable for: WB
- Reacts with: Mouse, Human, Saccharomyces cerevisiae
- Isotype: IgG
製品名Anti-Retinoic Acid Receptor beta antibody
Retinoic Acid Receptor beta 一次抗体 製品一覧
製品の詳細Rabbit polyclonal to Retinoic Acid Receptor beta
特異性This antibody shows slight cross-reactivity to RAR alpha but does not detect RAR gamma.
アプリケーション適用あり: WBmore details
種交差性交差種: Mouse, Human, Saccharomyces cerevisiae
- SH-SY5Y cell extract.
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
バッファーPreservative: 0.05% Sodium azide
Constituent: 99% PBS
Concentration information loading...
- Signal Transduction
- Signaling Pathway
- Nuclear Signaling
- Nuclear Hormone Receptors
- Retinoic & Retinoid
Our Abpromise guarantee covers the use of ab5792 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/1000. Detects a band of approximately 52 kDa (predicted molecular weight: 53 kDa).|
機能Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence or presence of hormone ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. In concert with RARG, required for skeletal growth, matrix homeostasis and growth plate function.
関連疾患Microphthalmia, syndromic, 12
配列類似性Belongs to the nuclear hormone receptor family. NR1 subfamily.
Contains 1 nuclear receptor DNA-binding domain.
ドメインComposed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
細胞内局在Cytoplasm and Nucleus.
- Information by UniProt
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All lanes : Anti-Retinoic Acid Receptor beta antibody (ab5792) at 1/1000 dilution
Lane 1 : SH-SY5Y cell lysate
Lane 2 : HepG2 cell lysate
Lane 3 : Mouse heart cell lysate
Lysates/proteins at 25 µg per lane.
Predicted band size: 53 kDa
Observed band size: 58 kDa why is the actual band size different from the predicted?