Anti-Retinoic Acid Receptor beta 抗体 (ab5792)

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Western blot - Anti-Retinoic Acid Receptor beta antibody (ab5792)

    Key features and details

    • Rabbit polyclonal to Retinoic Acid Receptor beta
    • Suitable for: WB
    • Reacts with: Mouse, Human, Saccharomyces cerevisiae
    • Isotype: IgG

    製品の概要

    • 製品名

      Anti-Retinoic Acid Receptor beta antibody
      Retinoic Acid Receptor beta 一次抗体 製品一覧

    • 製品の詳細

      Rabbit polyclonal to Retinoic Acid Receptor beta

    • 由来種

      Rabbit

    • 特異性

      This antibody shows slight cross-reactivity to RAR alpha but does not detect RAR gamma.

    • アプリケーション

      適用あり: WBmore details

    • 種交差性

      交差種: Mouse, Human, Saccharomyces cerevisiae

    • 免疫原

      Synthetic peptide corresponding to Mouse Retinoic Acid Receptor beta aa 429-448.
      Sequence:

      PSUSPSSVENSGVSQSPLLQ


      (Peptide available as ab5897)
      Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI

    • ポジティブ･コントロール

      • SH-SY5Y cell extract.

    • 特記事項

      Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.

      Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.

      We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.

      In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.

      We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.

      Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.

      Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.

    製品の特性

    アプリケーション

    Our Abpromise guarantee covers the use of ab5792 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    アプリケーション Abreviews 特記事項
    WB 1/1000. Detects a band of approximately 52 kDa (predicted molecular weight: 53 kDa).

    ターゲット情報

    • 機能

      Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence or presence of hormone ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. In concert with RARG, required for skeletal growth, matrix homeostasis and growth plate function.

    • 関連疾患

      Microphthalmia, syndromic, 12

    • 配列類似性

      Belongs to the nuclear hormone receptor family. NR1 subfamily.
      Contains 1 nuclear receptor DNA-binding domain.

    • ドメイン

      Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.

    • 細胞内局在

      Cytoplasm and Nucleus.
    • Information by UniProt

    • 参照データベース

      see all

    • 別名

      • HAP antibody
      • HBV-activated protein antibody
      • NR1B2 antibody
      • Nuclear receptor subfamily 1 group B member 2 antibody
      • RAR B antibody
      • RAR beta antibody
      • RAR epsilon antibody
      • RAR-beta antibody
      • RAR-epsilon antibody
      • RARB antibody
      • RARB_HUMAN antibody
      • Retinoic acid receptor beta 2 antibody
      • Retinoic acid receptor beta 4 antibody
      • Retinoic acid receptor beta 5 antibody
      • Retinoic acid receptor beta antibody
      • Retinoic acid receptor beta polypeptide antibody
      • RRB2 antibody
      see all

    画像

    • Western blot - Anti-Retinoic Acid Receptor beta antibody (ab5792)
      Western blot - Anti-Retinoic Acid Receptor beta antibody (ab5792)
      All lanes : Anti-Retinoic Acid Receptor beta antibody (ab5792) at 1/1000 dilution

      Lane 1 : SH-SY5Y cell lysate
      Lane 2 : HepG2 cell lysate
      Lane 3 : Mouse heart cell lysate

      Lysates/proteins at 25 µg per lane.

      Predicted band size: 53 kDa
      Observed band size: 58 kDa
      why is the actual band size different from the predicted?

    参考文献 (0)

    ab5792 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

    ab5792 は論文での使用が確認できていません。

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    1-2 of 2 Abreviews or Q&A

    Immunohistochemistry (Frozen sections) abreview for Anti-Retinoic Acid Receptor beta antibody

     Poor
    Abreviews
    abreview image
    Application
    Immunohistochemistry (Frozen sections)
    Sample
    Mouse Tissue sections (brain)
    Specification
    brain
    Fixative
    Paraformaldehyde
    Permeabilization
    Yes - Triton 100x
    Blocking step
    Serum as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 10% · Temperature: 21°C
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    Abcam user community

    Verified customer

    投稿 Mar 29 2012

    Question

    send testing discount for ab5792 in IHC

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    Answer

    Code de remise :xx Date d’expiration : 14. Juin 2012

    Je suis ravie que vous souhaitiez participer a notre offre et tester ab5792 en IHC. Le code de réduction correspondant est xx. Ce code de réduction est utilisable sous 120 jours et pour l’achat d’un autre anticorps primaire.

    Vous devez dans un premier temps soumettre une Abreview avec vos résultats en IHC en notant ce code dans la section « Additional notes ». Ce code sera ainsi activé et vous pourrez par la suite contacter notre service clientèle par téléphone pour passer votre prochaine commande, en vous munissant des informations suivantes : code de réduction, numéro de commande de ab5792.

    Nous restons à votre disposition pour plus d’informations concernant cette offre promotionnelle. Dans l’attente de recevoir votre Abreview nous vous souhaitons bonne chance dans vos recherches.

    Termes et Conditions : www.abcam.com/collaborationdiscount.

    Read More

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