製品名Recombinant T. gondii Toxoplasma gondii p30 protein
Toxoplasma gondii p30 タンパク質・ペプチド 製品一覧
領域45 to 198
Our Abpromise guarantee covers the use of ab119459 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
精製度> 95 % SDS-PAGE.
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Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Constituents: 9% Urea, 0.79% Tris HCl, 50% Glycerol
- Major surface antigen p30
- SAG1 protein
関連性Toxoplasma gondii p30 is the immunodominant surface antigen of Toxoplasma gondii. Toxoplasma gondii is an obligate intracellular protozoan that belongs to the class Sporozoa, and the order Eucoccidia. The parasite has an extremely wide host range and is also nonspecific with respect to the kind of cell type it can enter, making it an interesting model to study invasion. Although toxoplasmosis in healthy adults is generally asymptomatic, it produces severe disease in neonates and immunocompromised people, being the cause of death in many AIDS patients. P30 is the major surface antigen of T. gondii. It is a very abundant protein, conserved in most strains, and present both in the vesicular network of the parasitophorous vacuole and on the surface of the parasite. It is very immunogenic, eliciting high titers of antibodies in infected individuals. The gene coding for P30 has been cloned and completely sequenced: the deduced amino acid sequence shows a putative signal sequence at the N terminus, consistent with localization of P30 on the parasite’s surface, as well as a short hydrophobic stretch at the C terminus.
ab119459 has not yet been referenced specifically in any publications.