Key features and details
- Expression system: Escherichia coli
- Purity: > 98% SDS-PAGE
- Active: Yes
- Suitable for: Functional Studies, SDS-PAGE
- High batch-to-batch consistency
- Optimal bioactivity
- Guaranteed identical to human native proteins
- >95% purity
- Ultra-low endotoxin levels: <0.005 Eu/µg
- Carrier and tag free
製品名Recombinant rat IL-4 protein
IL-4 タンパク質・ペプチド 製品一覧
Determined by its ability to stimulate rat NB2-11 cell survival in low serum conditions using a concentration range of 3.0-7.0 ng/ml.
精製度> 98 % SDS-PAGE.
Sterile filtered Greater than 98% pure by HPLC analyses. Endotoxin level is less than 0.1 g/ml (1EU/g).
タンパク質長Full length protein
配列MHGCNDSPLREIINTLNQVTEKGTPCTEMFVPDVLTATRNTTENELICRA SRVLRKFYFPRDVPPCLKNKSGVLGELRKLCRGVSGLNSLRSCTVNESTL TTLKDFLESLKSILRGKYLQSCTSMS
領域22 to 147
Our Abpromise guarantee covers the use of ab9812 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Biological Activity: Tested by its ability to stimulate proliferation of TF-1 cells. The expected ED50 is 200-400 ng/ml
Concentration information loading...
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
This product is an active protein and may elicit a biological response in vivo, handle with caution.
再構成For lot specific reconstitution information please contact our Scientific Support Team.
- B cell growth factor 1
- B cell IgG differentiation factor
- B Cell Stimulatory Factor 1
機能Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes.
関連疾患Genetic variations in IL4 may be a cause of susceptibility to ischemic stroke (ISCHSTR) [MIM:601367]; also known as cerebrovascular accident or cerebral infarction. A stroke is an acute neurologic event leading to death of neural tissue of the brain and resulting in loss of motor, sensory and/or cognitive function. Ischemic strokes, resulting from vascular occlusion, is considered to be a highly complex disease consisting of a group of heterogeneous disorders with multiple genetic and environmental risk factors.
配列類似性Belongs to the IL-4/IL-13 family.
- Information by UniProt
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.