Recombinant Mouse TIGIT protein (Tagged) (Biotin) (ab271760)
Key features and details
- Expression system: HEK 293 cells
- Purity: >= 90% SDS-PAGE
- Tags: Avi tag N-Terminus, Fc tag N-Terminus
- Suitable for: WB, SDS-PAGE
製品の詳細
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製品名
Recombinant Mouse TIGIT protein (Tagged) (Biotin)
TIGIT タンパク質・ペプチド 製品一覧 -
精製度
>= 90 % SDS-PAGE. -
発現系
HEK 293 cells -
アクセッション番号
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タンパク質長
Protein fragment -
Animal free
No -
由来
Recombinant -
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生物種
Mouse -
配列
TAGTIDTKRNISAEEGGSVILQCHFSSDTAEVTQVDWKQQDQLLAIYSVD LGWHVASVFSDRVVPGPSLGLTFQSLTMNDTGEYFCTYHTYPGGIYKGRI FLKVQESSDDRNGLAQFQ -
分子量情報
42 kDa by SDS-PAGE -
領域
26 to 143 -
タグ
Avi tag N-Terminus , Fc tag N-Terminus
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標識
Biotin
特性
Our Abpromise guarantee covers the use of ab271760 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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アプリケーション
Western blot
SDS-PAGE
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製品の状態
Liquid -
備考
Enzymatically biotin-labeled using Avi-tag™ technology
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Concentration information loading...
前処理および保存
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保存方法および安定性
Shipped on Dry Ice. Store at -80°C. Avoid freeze / thaw cycle. Store In the Dark.
pH: 7.40
Constituents: 0.02% Sodium phosphate, 0.64% Sodium chloride, 0.02% Potassium chloride, 20% Glycerol (glycerin, glycerine)
関連情報
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別名
- DKFZp667A205
- ENSMUSG00000071552
- FLJ39873
see all -
機能
Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells. -
組織特異性
Expressed at low levels on peripheral memory and regulatory CD4+ T cells and NK cells and is up-regulated following activation of these cells (at protein level). -
配列類似性
Contains 1 Ig-like V-type (immunoglobulin-like) domain. -
ドメイン
Contains 1 copy of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in modulation of cellular responses. The phosphorylated ITIM motif can bind the SH2 domain of several SH2-containing phosphatases. -
細胞内局在
Cell membrane. - Information by UniProt
画像
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SDS-PAGE - Recombinant Mouse TIGIT protein (Tagged) (Biotin) (ab271760)
SDS-PAGE analysis of 5 µg ab271760.
This protein runs at a higher MW by SDS-PAGE due to glycosylation.
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Western blot - Recombinant Mouse TIGIT protein (Tagged) (Biotin) (ab271760)Recombinant Mouse TIGIT protein (Tagged) (Biotin) (ab271760) at 5 µg
Predicted band size: 26 kDa
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
参考文献 (0)
ab271760 は論文での使用が確認できていません。
