Recombinant mouse PDE6C protein (Active) (ab271683)
Key features and details
- Expression system: Baculovirus infected Sf9 cells
- Purity: >= 2% SDS-PAGE
- Active: Yes
- Tags: GST tag N-Terminus
- Suitable for: SDS-PAGE, Functional Studies
製品の詳細
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製品名
Recombinant mouse PDE6C protein (Active)
PDE6C タンパク質・ペプチド 製品一覧 -
生理活性
Specific Activity ≥ 600 pmol/min/µg.Unit Definition: One unit is defined as the amount of enzyme that will convert 1 pmole of 3′, 5′-cGMP to 5′-GMP per min at 37°C. -
精製度
>= 2 % SDS-PAGE. -
発現系
Baculovirus infected Sf9 cells -
アクセッション番号
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タンパク質長
Full length protein -
Animal free
No -
由来
Recombinant -
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生物種
Mouse -
予測される分子量
126 kDa -
領域
2 to 861 -
タグ
GST tag N-Terminus
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特性
Our Abpromise guarantee covers the use of ab271683 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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アプリケーション
SDS-PAGE
Functional Studies
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製品の状態
Liquid -
Concentration information loading...
前処理および保存
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保存方法および安定性
Shipped on Dry Ice. Store at -80°C. Avoid freeze / thaw cycle.
pH: 8.00
Constituents: 0.63% Tris HCl, 0.64% Sodium chloride, 0.02% Potassium chloride, 0.31% Glutathione, 0.05% (R*,R*)-1,4-Dimercaptobutan-2,3-diol, 20% Glycerol (glycerin, glycerine)This product is an active protein and may elicit a biological response in vivo, handle with caution.
関連情報
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別名
- 5''-cyclic phosphodiesterase subunit alpha''
- cGMP phosphodiesterase 6C
- COD4
see all -
関連疾患
Defects in PDE6C are the cause of cone dystrophy type 4 (COD4) [MIM:613093]. An early-onset cone dystrophy. Cone dystrophies are retinal dystrophies characterized by progressive degeneration of the cone photoreceptors with preservation of rod function, as indicated by electroretinogram. However, some rod involvement may be present in some cone dystrophies, particularly at late stage. Affected individuals suffer from photophobia, loss of visual acuity, color vision and central visual field. Another sign is the absence of macular lesions for many years. Cone dystrophies are distinguished from the cone-rod dystrophies in which some loss of peripheral vision also occurs. -
配列類似性
Belongs to the cyclic nucleotide phosphodiesterase family.
Contains 2 GAF domains. -
細胞内局在
Cell membrane. - Information by UniProt
画像
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SDS-PAGE - Recombinant mouse PDE6C protein (Active) (ab271683)
Specific activity of ab271683 was ≥ 600 pmol/min/µg.
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SDS-PAGE - Recombinant mouse PDE6C protein (Active) (ab271683)SDS-PAGE analysis of ab271683.
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
参考文献 (0)
ab271683 は論文での使用が確認できていません。
