Recombinant mouse IL-13 protein (Active) (ab270080)
Key features and details
- Expression system: HEK 293 cells
- Purity: >= 95% Immunogen affinity purified
- Endotoxin level: < 0.005 Eu/µg
- Active: Yes
- Suitable for: Cell Culture, Functional Studies, HPLC, MS, SDS-PAGE
製品の詳細
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製品名
Recombinant mouse IL-13 protein (Active)
IL-13 タンパク質・ペプチド 製品一覧 -
生理活性
Fully biologically active when compared to standard. Determined by the dose dependant proliferation of TF-1 cell line.
ED50 is ≤ 1.892 ng/mL, corresponding to a specific activity of 5.29 x 105 units/mg.
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精製度
>= 95 % Immunogen affinity purified.
Purity by HPLC >=95%. -
エンドトキシン・レベル
< 0.005 Eu/µg -
発現系
HEK 293 cells -
アクセッション番号
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タンパク質長
Full length protein -
Animal free
No -
キャリア・フリー
はい -
由来
Recombinant -
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生物種
Mouse -
予測される分子量
12 kDa -
分子量情報
M+1.63 Da, pass (+655 Da: Hex(1)HexNAc(1)NeuAc(1)). Calc MW 12409.37 Da APGPVPRSVS LPLTLKELIE ELSNITQDQT PLCNGSMVWS VDLAAGGFCV ALDSLTNISN CNAIYRTQRI LHGLCNRKAP TTVSSLPDTK IEVAHFITKL LSYTKQLFRH GPF -
領域
19 to 131 -
配列の追加情報
N-terminal glycine Full-length mature chain lacking the signal peptide.
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関連製品
特性
Our Abpromise guarantee covers the use of ab270080 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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アプリケーション
Cell Culture
Functional Studies
HPLC
Mass Spectrometry
SDS-PAGE
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製品の状態
Lyophilized -
備考
This protein is filter sterilised prior to aliquoting and lyophilisation. All aliquoting and lyophilisation steps are performed in a sterile environment
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Concentration information loading...
前処理および保存
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保存方法および安定性
Shipped at Room Temperature. Store at Room Temperature.
Information available upon request.
This product is an active protein and may elicit a biological response in vivo, handle with caution.
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再構成Reconstitute with phosphate buffered saline. Store lyophilized form at room temperature. Reconstitute, aliquot and store at -80°C for 12 months or +4°C for 1 week. Avoid repeated freeze-thaw.
関連情報
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別名
- Allergic rhinitis
- ALRH
- BHR 1
see all -
機能
Cytokine (PubMed:8096327, PubMed:8097324). Inhibits inflammatory cytokine production (PubMed:8096327). Synergizes with IL2 in regulating interferon-gamma synthesis (PubMed:8096327). May be critical in regulating inflammatory and immune responses (PubMed:8096327, PubMed:8097324). Positively regulates IL31RA expression in macrophages. -
関連疾患
Allergic rhinitis -
配列類似性
Belongs to the IL-4/IL-13 family. -
細胞内局在
Secreted. - Information by UniProt
画像
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Functional Studies - Recombinant mouse IL-13 protein (Active) (ab270080)
Fully biologically active when compared to standard. Determined by the dose dependant proliferation of TF-1 cell line.
ED50 is ≤ 1.892 ng/mL, corresponding to a specific activity of 5.29 x 105 units/mg.
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SDS-PAGE - Recombinant mouse IL-13 protein (Active) (ab270080)SDS-PAGE analysis of ab270080.The protein has multiple N-linked glycosylations. -
HPLC - Recombinant mouse IL-13 protein (Active) (ab270080)Purity by HPLC ≥95%.
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Mass Spectrometry - Recombinant mouse IL-13 protein (Active) (ab270080)M+1.63 Da, pass (+655 Da: Hex(1)HexNAc(1)NeuAc(1)). Calc MW 12409.37 Da
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab270080 は論文での使用が確認できていません。