Recombinant Mouse Fibroblast activation protein, alpha (Tagged) (ab271506)
Key features and details
- Expression system: HEK 293 cells
- Purity: = 90% SDS-PAGE
- Tags: His tag C-Terminus
- Suitable for: SDS-PAGE
製品の詳細
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製品名
Recombinant Mouse Fibroblast activation protein, alpha (Tagged)
Fibroblast activation protein, alpha タンパク質・ペプチド 製品一覧 -
精製度
= 90 % SDS-PAGE. -
発現系
HEK 293 cells -
アクセッション番号
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タンパク質長
Full length protein -
Animal free
No -
由来
Recombinant -
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生物種
Mouse -
配列
LRPSRVYKPE GNTKRALTLK DILNGTFSYK TYFPNWISEQ EYLHQSEDDN IVFYNIETRE SYIILSNSTM KSVNATDYGL SPDRQFVYLE SDYSKLWRYS YTATYYIYDL QNGEFVRGYE LPRPIQYLCW SPVGSKLAYV YQNNIYLKQR PGDPPFQITY TGRENRIFNG IPDWVYEEEM LATKYALWWS PDGKFLAYVE FNDSDIPIIA YSYYGDGQYP RTINIPYPKA GAKNPVVRVF IVDTTYPHHV GPMEVPVPEM IASSDYYFSW LTWVSSERVC LQWLKRVQNV SVLSICDFRE DWHAWECPKN QEHVEESRTG WAGGFFVSTP AFSQDATSYY KIFSDKDGYK HIHYIKDTVE NAIQITSGKW EAIYIFRVTQ DSLFYSSNEF EGYPGRRNIY RISIGNSPPS KKCVTCHLRK ERCQYYTASF SYKAKYYALV CYGPGLPIST LHDGRTDQEI QVLEENKELE NSLRNIQLPK VEIKKLKDGG LTFWYKMILP PQFDRSKKYP LLIQVYGGPC SQSVKSVFAV NWITYLASKE GIVIALVDGR GTAFQGDKFL HAVYRKLGVY EVEDQLTAVR KFIEMGFIDE ERIAIWGWSY GGYVSSLALA SGTGLFKCGI AVAPVSSWEY YASIYSERFM GLPTKDDNLE HYKNSTVMAR AEYFRNVDYL LIHGTADDNV HFQNSAQIAK ALVNAQVDFQ AMWYSDQNHG ISSGRSQNHL YTHMTHFLKQ CFSLSD -
予測される分子量
88 kDa including tags -
領域
26 to 761 -
タグ
His tag C-Terminus -
配列の追加情報
Genbank: NM_007986
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特性
Our Abpromise guarantee covers the use of ab271506 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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アプリケーション
SDS-PAGE
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製品の状態
Liquid -
Concentration information loading...
前処理および保存
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保存方法および安定性
Shipped on Dry Ice. Store at -80°C. Avoid freeze / thaw cycle.
pH: 7.40
Constituents: 0.13% Sodium phosphate, 1.61% Sodium chloride, 0.02% Potassium chloride, 20% Glycerol (glycerin, glycerine)
関連情報
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別名
- 170 kDa melanoma membrane bound gelatinase
- 170 kDa melanoma membrane-bound gelatinase
- DPPIV
see all -
機能
In association with DPP4 is involved in the pericellular proteolysis of the extracellular matrix (ECM), the migration and invasion of endothelial cells into the ECM. May have a role in tissue remodeling during development and wound healing, and may contribute to invasiveness in malignant cancers. -
組織特異性
Fibroblast specific. -
配列類似性
Belongs to the peptidase S9B family. -
翻訳後修飾
N-glycosylated.
The N-terminus may be blocked. -
細胞内局在
Cell membrane. Cell projection > lamellipodium membrane. Cell projection > invadopodium membrane. Found in cell surface lamellipodia, invadopodia and on shed vesicles. Colocalized with DPP4 in invadopodia and lamellipodia of migratory activated endothelial cells in collagenous matrix. Colocalized with DPP4 on endothelial cells of capillary-like microvessels but not large vessels within invasive breast ductal carcinoma. - Information by UniProt
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プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab271506 は論文での使用が確認できていません。