The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
% SDS-PAGE. ab74970 is purified by using conventional chromatography techniques.
Concentration information loading...
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.242% Tris, 10% Glycerol
Alpha B crystallin
Alpha crystallin B chain
Alpha-crystallin B chain
Crystallin alpha B
Crystallin alpha polypeptide 2
Heat shock 20 kD like protein
Heat shock protein beta 5
Heat shock protein beta-5
Renal carcinoma antigen NY REN 27
Renal carcinoma antigen NY-REN-27
Rosenthal fiber component
May contribute to the transparency and refractive index of the lens.
Lens as well as other tissues.
Defects in CRYAB are the cause of myofibrillar alpha-B crystallin-related (MFM-CRYAB) [MIM:608810]. A neuromuscular disorder that results in weakness of the proximal and distal limb muscles, weakness of the neck, velopharynx and trunk muscles, hypetrophic cardiomyopathy, and cataract in a subset of patients.
Belongs to the small heat shock protein (HSP20) family.
Cytoplasm. Nucleus. Translocates to the nucleus during heat shock and resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles.