Key features and details
- Expression system: Baculovirus
- Purity: > 70% SDS-PAGE
- Active: Yes
- Suitable for: SDS-PAGE, Functional Studies
製品名Recombinant human VEGF Receptor 3 protein
VEGF Receptor 3 タンパク質・ペプチド 製品一覧
Specific Activity: 17 pmol/min/µg. Assay conditions: VEGFR3 was incubated with a substrate (Tyr peptide 4 for 1h at RT in 1Xkinase buffer supplemented with ATP. Developer solution was added to reaction and reaction was stopped after 1h of incubation at RT.
精製度> 70 % SDS-PAGE.
領域798 to 1298
Our Abpromise guarantee covers the use of ab95247 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Concentration information loading...
Shipped on Dry Ice. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.
Constituents: 0.0462% (R*,R*)-1,4-Dimercaptobutan-2,3-diol, 0.395% Tris HCl, 0.05% Tween, 20% Glycerol (glycerin, glycerine), 0.8004% Sodium chloride
This product is an active protein and may elicit a biological response in vivo, handle with caution.
- EC 188.8.131.52
- flt 4
機能Receptor for VEGFC. Has a tyrosine-protein kinase activity.
組織特異性Placenta, lung, heart, and kidney, does not seem to be expressed in pancreas and brain.
関連疾患Defects in FLT4 are the cause of lymphedema hereditary type 1A (LMPH1A) [MIM:153100]; also known as Nonne-Milroy lymphedema or Milroy disease. Hereditary lymphedema is a chronic disabling condition which results in swelling of the extremities due to altered lymphatic flow. Patients with lymphedema suffer from recurrent local infections and physical impairment.
Note=Defects in FLT4 are found in juvenile hemangioma. Juvenile hemangiomas are the most common tumors of infancy, occurring as many as 10% of all births. These benign vascular lesions enlarge rapidly during the first year of life by hyperplasia of endothelial cells and attendant pericytes, and then spontaneously involute over a period of years, leaving loose fibrofatty tissue.
配列類似性Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
Contains 7 Ig-like C2-type (immunoglobulin-like) domains.
Contains 1 protein kinase domain.
- Information by UniProt
The specific activity of ab95247 was found to be 17 pmol/min/µg by carrying out functional studies. The assay conditions were; VEGFR3 was incubated with a substrate (Tyr peptide 4) for 1h at RT in 1Xkinase buffer supplemented with ATP. Developer solution was added to reaction and reaction was stopped after 1h of incubation at RT.
ab95247 was analysed by SDS-PAGE. Lane 1; ab95247 at 4µg. Lane 2; protein molecular weight markers. ab95247 has a predicted molecular weight of 82 kDa and is >70% pure as assessed by SDS-PAGE.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.