Recombinant Human USP3 protein (ab127142)
Key features and details
- Expression system: Escherichia coli
- Purity: > 85% SDS-PAGE
- Tags: His-DHFR tag N-Terminus
- Suitable for: SDS-PAGE
製品の詳細
-
製品名
Recombinant Human USP3 protein -
精製度
> 85 % SDS-PAGE.
Purified via His tag -
発現系
Escherichia coli -
アクセッション番号
-
タンパク質長
Protein fragment -
Animal free
No -
由来
Recombinant -
-
生物種
Human -
予測される分子量
24 kDa -
領域
313 to 520 -
タグ
His-DHFR tag N-Terminus
-
関連製品
-
Related Products
特性
Our Abpromise guarantee covers the use of ab127142 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
-
アプリケーション
SDS-PAGE
-
製品の状態
Lyophilized -
Concentration information loading...
前処理および保存
-
保存方法および安定性
Shipped at 4°C. Store at -20ºC.
Constituents: 0.32% Tris HCl, 0.58% Sodium chloride
-
再構成Reconstitute with water to desired concentration.
関連情報
-
別名
- Deubiquitinating enzyme 3
- EC 3.1.2.15
- SIH003
see all -
機能
Hydrolase that deubiquitinates monoubiquitinated target proteins such as histone H2A and H2B. Required for proper progression through S phase and subsequent mitotic entry. May regulate the DNA damage response (DDR) checkpoint through deubiquitination of H2A at DNA damage sites. Associates with the chromatin. -
組織特異性
Expressed in all tissues examined, with strongest expression in pancreas. -
配列類似性
Belongs to the peptidase C19 family. USP3 subfamily.
Contains 1 UBP-type zinc finger. -
ドメイン
Both protease activity and an intact zinc finger are required for H2A monodeubiquitination. -
細胞内局在
Nucleus. Localizes preferentially with monoubiquitinated H2A to chromatin. - Information by UniProt
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
-
Datasheet download
参考文献 (0)
ab127142 は論文での使用が確認できていません。