Recombinant human SIRT2 protein (ab101132)
Key features and details
- Expression system: Baculovirus infected insect cells
- Purity: > 70% Densitometry
- Active: Yes
- Tags: His tag N-Terminus
- Suitable for: SDS-PAGE, Functional Studies
製品の詳細
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製品名
Recombinant human SIRT2 protein
SIRT2 タンパク質・ペプチド 製品一覧 -
生理活性
Specific Activity: 8000 RLU/min/ng.
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精製度
> 70 % Densitometry.
The purity of SIRT2 was determined to be > 70% by densitometry. Affinity purified. -
発現系
Baculovirus infected insect cells -
アクセッション番号
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タンパク質長
Full length protein -
Animal free
No -
由来
Recombinant -
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生物種
Human -
予測される分子量
42 kDa including tags -
領域
2 to 352 -
タグ
His tag N-Terminus
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関連製品
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Related Products
特性
Our Abpromise guarantee covers the use of ab101132 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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アプリケーション
SDS-PAGE
Functional Studies
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製品の状態
Liquid -
Concentration information loading...
前処理および保存
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保存方法および安定性
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 7.00
Preservative: 1.02% Imidazole
Constituents: 0.00174% PMSF, 0.82% Sodium phosphate, 0.00385% DTT, 25% Glycerol (glycerin, glycerine), 1.74% Sodium chlorideThis product is an active protein and may elicit a biological response in vivo, handle with caution.
関連情報
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別名
- FLJ35621
- FLJ37491
- NAD dependent deacetylase sirtuin 2
see all -
機能
NAD-dependent protein deacetylase, which deacetylates the 'Lys-40' of alpha-tubulin. Involved in the control of mitotic exit in the cell cycle, probably via its role in the regulation of cytoskeleton. -
組織特異性
Widely expressed. Highly expressed in heart, brain and skeletal muscle, while it is weakly expressed in placenta and lung. Down-regulated in many gliomas suggesting that it may act as a tumor suppressor gene in human gliomas possibly through the regulation of microtubule network. -
配列類似性
Belongs to the sirtuin family.
Contains 1 deacetylase sirtuin-type domain. -
発生段階
Peaks during mitosis. After mitosis, it is probably degraded by the 26S proteasome. -
翻訳後修飾
Phosphorylated at the G2/M transition of the cell cycle. -
細胞内局在
Cytoplasm > cytoskeleton. Colocalizes with microtubules. - Information by UniProt
画像
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab101132 は論文での使用が確認できていません。