Recombinant Human SARM protein (Tagged) (ab271737)

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Western blot - Recombinant Human SARM protein (Tagged) (ab271737)
  • SDS-PAGE - Recombinant Human SARM protein (Tagged) (ab271737)

Key features and details

  • Expression system: HEK 293 cells
  • Purity: >= 90% SDS-PAGE
  • Tags: DDDDK tag N-Terminus
  • Suitable for: SDS-PAGE, WB

製品の詳細

  • 製品名

    Recombinant Human SARM protein (Tagged)
    SARM タンパク質・ペプチド 製品一覧

  • 精製度

    >= 90 % SDS-PAGE.

  • 発現系

    HEK 293 cells

  • アクセッション番号

    Q6SZW1

  • タンパク質長

    Full length protein

  • Animal free

    No

  • 由来

    Recombinant

    • 生物種

      Human

    • 予測される分子量

      77 kDa

    • 領域

      28 to 724

    • タグ

      DDDDK tag N-Terminus

    • 配列の追加情報

      Mature chain.

特性

Our Abpromise guarantee covers the use of ab271737 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

    Western blot

  • 製品の状態

    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on Dry Ice. Store at -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.63% Tris HCl, 0.64% Sodium chloride, 0.02% Potassium chloride, 20% Glycerol (glycerin, glycerine), 0.05% (R*,R*)-1,4-Dimercaptobutan-2,3-diol

    100ug/ml DDDDK peptide.

関連情報

  • 別名

    • FLJ36296
    • KIAA0524
    • MyD88-5
    • SAM and ARM-containing protein
    • SAM domain-containing protein 2
    • SAMD2
    • SARM 1
    • SARM1
    • SARM1_HUMAN
    • Sterile alpha and Armadillo repeat protein
    • sterile alpha and HEAT/Armadillo motif protein, ortholog of Drosophila
    • sterile alpha and HEAT/Armadillo motifs-containing protein
    • sterile alpha and TIR motif containing 1
    • Sterile alpha and TIR motif-containing protein 1
    • Sterile alpha and TIR motifs-containing protein 1
    • Sterile alpha motif domain-containing protein 2
    • Tir-1 homolog
    see all

  • 機能

    Involved in innate immnune response. Acts as a negative regulator of TICAM1/TRIF-dependent Toll-like receptor signaling by inhibiting induction of TLR3- and TLR4-dependent genes. Specifically blocks TICAM1/TRIF-dependent transcription-factor activation and gene induction, without affecting the MYD88-dependent pathway or non-TLR signaling. Negative regulator of NF-kappa-B and IRF activation.

  • 組織特異性

    Predominantly expressed in kidney and liver. Expressed at lower level in placenta.

  • 配列類似性

    Contains 2 SAM (sterile alpha motif) domains.
    Contains 1 TIR domain.

  • 細胞内局在

    Cytoplasm.
  • Information by UniProt

画像

  • Western blot - Recombinant Human SARM protein (Tagged) (ab271737)
    Western blot - Recombinant Human SARM protein (Tagged) (ab271737)

    Recombinant Human SARM protein (Tagged) (ab271737) used as positive control in WB.

  • SDS-PAGE - Recombinant Human SARM protein (Tagged) (ab271737)
    SDS-PAGE - Recombinant Human SARM protein (Tagged) (ab271737)

    SDS-PAGE analysis of ab271737.

プロトコール

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

参考文献 (0)

ab271737 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

ab271737 は論文での使用が確認できていません。

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