製品の概要

  • 製品名
    Recombinant Human RAP1B protein
  • タンパク質長
    Full length protein

製品の詳細

  • 由来
    Recombinant
  • 由来
    Escherichia coli
  • アミノ酸配列
    • アクセッション番号
      P61224
    • 生物種
      Human
    • 配列
      MGSSHHHHHHSSGLVPRGSHMREYKLVVLGSGGVGKSALTVQFVQGIFVE KYDPTIEDSYRKQVEVDAQQCMLEILDTAGTEQFTAMRDLYMKNGQGFAL VYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLEDERVVGKEQ GQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINRKTPVPGKARKKSS C
    • 分子量
      23 kDa including tags
    • 領域
      1 to 181
    • タグ
      His tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab103049 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

    Mass Spectrometry

  • 質量分析
    MALDI-TOF
  • 精製度
    > 90 % SDS-PAGE.
    ab103049 was purified using conventional chromatography techniques.
  • 製品の状態
    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 20% Glycerol, 0.2M Sodium chloride, 5mM DTT, 20mM Tris HCl, pH 8.0

関連情報

  • 別名
    • GTP-binding protein smg p21B
    • K-REV
    • OK/SW-cl.11
    • RAL1B
    • rap1b
    • RAP1B member of RAS oncogene family
    • RAP1B_HUMAN
    • Ras family small GTP binding protein RAP1B
    • RAS related protein RAP1B
    • Ras-related protein Rap-1b
    • Small GTP binding protein
    see all
  • 機能
    GTP-binding protein that possesses intrinsic GTPase activity. Contributes to the polarizing activity of KRIT1 and CDH5 in the establishment and maintenance of correct endothelial cell polarity and vascular lumen. Required for the localization of phosphorylated PRKCZ, PARD3 and TIAM1 to the cell junction.
  • 配列類似性
    Belongs to the small GTPase superfamily. Ras family.
  • 細胞内局在
    Cell membrane. Cytoplasm > cytosol. Cell junction. May shuttle between plasma membrane and cytosol. Presence of KRIT1 and CDH5 is required for its localization to the cell junction.
  • Information by UniProt

画像

  • SDS-PAGE - RAP1B delta C protein (ab103049)
    SDS-PAGE - RAP1B delta C protein (ab103049)
    15% SDS-PAGE analysis of 3µg ab103049

参考文献

ab103049 has not yet been referenced specifically in any publications.

ab103049 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

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