Recombinant human PDGFR alpha (mutated D842Y) protein (Active) (ab271686)
Key features and details
- Expression system: Baculovirus infected Sf9 cells
- Purity: >= 90% SDS-PAGE
- Active: Yes
- Tags: GST tag N-Terminus
- Suitable for: SDS-PAGE, Functional Studies
製品の詳細
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製品名
Recombinant human PDGFR alpha (mutated D842Y) protein (Active)
PDGFR alpha タンパク質・ペプチド 製品一覧 -
生理活性
Specific Activity: 153 pmole/min/µg. -
精製度
>= 90 % SDS-PAGE. -
発現系
Baculovirus infected Sf9 cells -
アクセッション番号
-
タンパク質長
Protein fragment -
Animal free
No -
由来
Recombinant -
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生物種
Human -
予測される分子量
88 kDa -
領域
550 to 1089 -
修飾
mutated D842Y -
タグ
GST tag N-Terminus -
配列の追加情報
Cytoplasmic domain.
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関連製品
特性
Our Abpromise guarantee covers the use of ab271686 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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アプリケーション
SDS-PAGE
Functional Studies
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製品の状態
Liquid -
Concentration information loading...
前処理および保存
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保存方法および安定性
Shipped on Dry Ice. Store at -80°C. Avoid freeze / thaw cycle.
pH: 8.00
Constituents: 0.63% Tris HCl, 0.64% Sodium chloride, 0.02% Potassium chloride, 0.04% Tween, 0.05% (R*,R*)-1,4-Dimercaptobutan-2,3-diol, 20% Glycerol (glycerin, glycerine)This product is an active protein and may elicit a biological response in vivo, handle with caution.
関連情報
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別名
- Alpha-type platelet-derived growth factor receptor
- CD140 antigen-like family member A
- CD140a
see all -
機能
Receptor that binds both PDGFA and PDGFB and has a tyrosine-protein kinase activity. -
組織特異性
Expressed in primary and metastatic colon tumors and in normal colon tissue. Tumors may express a different isoform to that found in normal tissue. -
関連疾患
Note=A chromosomal aberration involving PDGFRA is found in some cases of hypereosinophilic syndrome. Interstitial chromosomal deletion del(4)(q12q12) causes the fusion of FIP1L1 and PDGFRA (FIP1L1-PDGFRA). -
配列類似性
Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
Contains 5 Ig-like C2-type (immunoglobulin-like) domains.
Contains 1 protein kinase domain. -
細胞内局在
Membrane. - Information by UniProt
画像
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SDS-PAGE - Recombinant human PDGFR alpha (mutated D842Y) protein (Active) (ab271686)
SDS-PAGE analysis of 2 µg ab271686.
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Functional Studies - Recombinant human PDGFR alpha (mutated D842Y) protein (Active) (ab271686)Specific activity of ab271686 was 153 pmole/min/µg.
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab271686 は論文での使用が確認できていません。