製品名Recombinant Human MAPKAP Kinase 2 protein
MAPKAP Kinase 2 タンパク質・ペプチド 製品一覧
タンパク質長Full length protein
由来Baculovirus infected Sf9 cells
Our Abpromise guarantee covers the use of ab79910 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Shipped on Dry Ice. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.
Constituents: 0.0462% DTT, 0.395% Tris HCl, 0.05% Tween, 50% Glycerol, 0.8004% Sodium chloride
- MAP kinase activated protein Kinase 2
- MAP kinase-activated protein kinase 2
- MAPK activated protein kinase 2
機能Its physiological substrate seems to be the small heat shock protein (HSP27/HSP25). In vitro can phosphorylate glycogen synthase at 'Ser-7' and tyrosine hydroxylase (on 'Ser-19' and 'Ser-40'). This kinase phosphorylates Ser in the peptide sequence, Hyd-X-R-X(2)-S, where Hyd is a large hydrophobic residue (By similarity). Mediates both ERK and p38 MAPK/MAPK14 dependent neutrophil responses. Participates in TNF alpha-stimulated exocytosis of secretory vesicles in neutrophils. Plays a role in phagocytosis-induced respiratory burst activity.
組織特異性Expressed in all tissues examined.
配列類似性Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
Contains 1 protein kinase domain.
翻訳後修飾Phosphorylated and activated by MAP kinase.
- Information by UniProt
ab79910 has not yet been referenced specifically in any publications.