Recombinant human LSD2 / AOF1 protein (Active) (ab271603)

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SDS-PAGE - Recombinant human LSD2 / AOF1 protein (Active) (ab271603)
  • SDS-PAGE - Recombinant human LSD2 / AOF1 protein (Active) (ab271603)

Key features and details

  • Expression system: Baculovirus infected Sf9 cells
  • Purity: >= 90% SDS-PAGE
  • Active: Yes
  • Suitable for: SDS-PAGE, Functional Studies

製品の詳細

  • 製品名

    Recombinant human LSD2 / AOF1 protein (Active)
    LSD2 / AOF1 タンパク質・ペプチド 製品一覧

  • 精製度

    >= 90 % SDS-PAGE.

  • 発現系

    Baculovirus infected Sf9 cells

  • アクセッション番号

    Q8NB78

  • タンパク質長

    Protein fragment

  • Animal free

    No

  • 由来

    Recombinant

    • 生物種

      Human

    • 予測される分子量

      121 kDa

    • 領域

      2 to 822

    • 配列の追加情報

      N-terminal GST-Tev tag.

特性

Our Abpromise guarantee covers the use of ab271603 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

    Functional Studies

  • 製品の状態

    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on Dry Ice. Store at -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.63% Tris HCl, 0.64% Sodium chloride, 0.02% Potassium chloride, 0.04% Tween, 20% Glycerol (glycerin, glycerine), 0.05% Glutathione

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

関連情報

  • 別名

    • amine oxidase (flavin containing) domain 1
    • amine oxidase, flavin containing 1
    • AOF1
    • bA204B7.3
    • C6orf193
    • dJ298J15.2
    • Flavin-containing amine oxidase domain-containing protein 1
    • FLJ33898
    • FLJ34109
    • FLJ43328
    • KDM1B
    • KDM1B_HUMAN
    • LSD2
    • lysine (K)-specific demethylase 1B
    • Lysine-specific demethylase 2
    • Lysine-specific histone demethylase 1B
    • Lysine-specific histone demethylase 2
    see all

  • 機能

    Histone demethylase that demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Required for de novo DNA methylation of a subset of imprinted genes during oogenesis. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Demethylates both mono- and di-methylated 'Lys-4' of histone H3. Has no effect on tri-methylated 'Lys-4', mono-, di- or tri-methylated 'Lys-9', mono-, di- or tri-methylated 'Lys-27', mono-, di- or tri-methylated 'Lys-36' of histone H3, or on mono-, di- or tri-methylated 'Lys-20' of histone H4.

  • 配列類似性

    Belongs to the flavin monoamine oxidase family.
    Contains 1 CW-type zinc finger.
    Contains 1 SWIRM domain.

  • ドメイン

    The SWIRM domain may act as an anchor site for a histone tail.

  • 細胞内局在

    Nucleus.
  • Information by UniProt

画像

  • SDS-PAGE - Recombinant human LSD2 / AOF1 protein (Active) (ab271603)
    SDS-PAGE - Recombinant human LSD2 / AOF1 protein (Active) (ab271603)

    SDS-PAGE analysis of ab271603.

  • SDS-PAGE - Recombinant human LSD2 / AOF1 protein (Active) (ab271603)
    SDS-PAGE - Recombinant human LSD2 / AOF1 protein (Active) (ab271603)

    Specific activity of ab271603.

プロトコール

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

参考文献 (0)

ab271603 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

ab271603 は論文での使用が確認できていません。

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