Recombinant Human ILT-3 protein (Tagged) (ab271597)

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SDS-PAGE - Recombinant Human ILT-3 protein (Tagged) (ab271597)

    Key features and details

    • Expression system: HEK 293 cells
    • Purity: >= 90% SDS-PAGE
    • Tags: Avi tag C-Terminus, Fc tag C-Terminus
    • Suitable for: SDS-PAGE

    製品の詳細

    • 製品名

      Recombinant Human ILT-3 protein (Tagged)
      ILT-3 タンパク質・ペプチド 製品一覧

    • 精製度

      >= 90 % SDS-PAGE.

    • 発現系

      HEK 293 cells

    • アクセッション番号

      Q8NHJ6

    • タンパク質長

      Protein fragment

    • Animal free

      No

    • 由来

      Recombinant

      • 生物種

        Human

      • 配列

        PRTH MQAGPLPKPT LWAEPGSVIS WGNSVTIWCQ GTLEAREYRL DKEESPAPWD RQNPLEPKNK ARFSIPSMTE DYAGRYRCYY RSPVGWSQPS DPLELVMTGA YSKPTLSALP SPLVTSGKSV TLLCQSRSPM DTFLLIKERA AHPLLHLRSE HGAQQHQAEF PMSPVTSVHG GTYRCFSSHG FSHYLLSHPS DPLELIVSGS LEDPRPSPTR SVSTAAGPED QPLMPTGSVP HSGLRRHWEV LIGVLVVSIL LLSLLLFLLL QHWRQGKHRT LAQRQADFQR PPGAAEPEPK DGGLQRRSSP AADVQGENFC AAVKNTQPED GVEMDTRQSP HDEDPQA

      • 予測される分子量

        31 kDa

      • 領域

        17 to 257

      • タグ

        Avi tag C-Terminus , Fc tag C-Terminus

    特性

    Our Abpromise guarantee covers the use of ab271597 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • アプリケーション

      SDS-PAGE

    • 製品の状態

      Liquid
    • Concentration information loading...

    前処理および保存

    • 保存方法および安定性

      Shipped on Dry Ice. Store at -80°C. Avoid freeze / thaw cycle.

      pH: 7.40
      Constituents: 0.13% Sodium phosphate, 0.64% Sodium chloride, 0.02% Potassium chloride, 20% Glycerol (glycerin, glycerine)

    関連情報

    • 別名

      • CD85 antigen-like family member K
      • CD85k
      • HM18
      • ILT-3
      • ILT3
      • Immunoglobulin-like transcript 3
      • Leukocyte immunoglobulin like receptor subfamily B (with TM and ITIM domains) member 4
      • Leukocyte immunoglobulin-like receptor 5
      • Leukocyte immunoglobulin-like receptor subfamily B member 4
      • LILRB4
      • LILRB5
      • LIR-5
      • LIR5
      • LIRB4_HUMAN
      • Monocyte inhibitory receptor HM18
      see all

    • 機能

      Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. Involved in the down-regulation of the immune response and the development of tolerance, e.g. towards transplants. Interferes with TNFRSF5-signaling and NF-kappa-B up-regulation. Inhibits receptor-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.

    • 組織特異性

      Detected in monocytes, macrophages, dendritic cells, lung, natural killer cells and B-cells.

    • 配列類似性

      Contains 2 Ig-like C2-type (immunoglobulin-like) domains.

    • ドメイン

      Contains 3 copies of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in modulation of cellular responses. The phosphorylated ITIM motif can bind the SH2 domain of several SH2-containing phosphatases.

    • 細胞内局在

      Cell membrane. Ligand binding leads to internalization and translocation to an antigen-processing compartment.
    • Information by UniProt

    画像

    • SDS-PAGE - Recombinant Human ILT-3 protein (Tagged) (ab271597)
      SDS-PAGE - Recombinant Human ILT-3 protein (Tagged) (ab271597)

      SDS-PAGE analysis of 4 µg ab271597.

    プロトコール

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    参考文献 (0)

    ab271597 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

    ab271597 は論文での使用が確認できていません。

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