Recombinant Human IL-31 protein (Active) (ab283936)
Key features and details
- Expression system: HEK 293 cells
- Purity: >= 95% SDS-PAGE
- Endotoxin level: < 0.005 Eu/µg
- Active: Yes
- Suitable for: Functional Studies, Cell Culture, SDS-PAGE, HPLC, MS
製品の詳細
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製品名
Recombinant Human IL-31 protein (Active)
IL-31 タンパク質・ペプチド 製品一覧 -
生理活性
Fully biologically active determined by its ability to induce STAT3 activation (phosphorylation Tyr705) in U-87 MG cells.
ED50 is ≤ 25.9 ng/ml, corresponding to a specific activity of 3.86 x 104 units/mg.
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精製度
>= 95 % SDS-PAGE.
Purity by HPLC =95% -
エンドトキシン・レベル
< 0.005 Eu/µg -
発現系
HEK 293 cells -
アクセッション番号
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タンパク質長
Full length protein -
Animal free
Yes -
キャリア・フリー
はい -
由来
Recombinant -
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生物種
Human -
配列
LPVRLLRPSD DVQKIVEELQ SLSKMLLKDV EEEKGVLVSQ NYTLPCLSPD AQPPNNIHSP AIRAYLKTIR QLDNKSVIDE IIEHLDKLIF QDAPETNISV PTDTHECKRF ILTISQQFSE CMDLALKSLT SGAQQATT -
予測される分子量
16 kDa -
実際の分子量
16 kDa -
分子量情報
Predicted MW is 15569.82 Da (+/- 10 Da by ESI TOF). Observed MW is 15571.44 Da. -
領域
27 to 164 -
配列の追加情報
Full-length mature chain lacking the signal peptide, N-terminal Glycine.
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製品の詳細
Recombinant Human IL-31 protein
特性
Our Abpromise guarantee covers the use of ab283936 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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アプリケーション
Functional Studies
Cell Culture
SDS-PAGE
HPLC
Mass Spectrometry
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製品の状態
Lyophilized -
Concentration information loading...
前処理および保存
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保存方法および安定性
Shipped at Room Temperature. Store at Room Temperature.
pH: 7.40
Constituents: 0.727% Dibasic monohydrogen potassium phosphate, 0.248% Monobasic dihydrogen potassium phosphate, 10.26% TrehaloseThis product is an active protein and may elicit a biological response in vivo, handle with caution.
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再構成Store lyophilized form at room temperature. Reconstitute, aliquot and store at -80°C for 12 months or +4°C for 1 week. Avoid repeated freeze-thaw. Lyophilized contents may appear as either a translucent film or a white powder. This variance does not affect the quality of the product. Lyophilized contents may appear as either a translucent film or a white powder. This variance does not affect the quality of the product.
関連情報
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別名
- IL 31
- IL-31
- IL31
see all -
機能
Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR. IL31 may function in skin immunity. -
組織特異性
Detected at low levels in testis, bone marrow, skeletal muscle, kidney, colon, thymus, small intestine and trachea. -
細胞内局在
Secreted. - Information by UniProt
画像
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Fully biologically active determined by its ability to induce STAT3 activation (phosphorylation Tyr705) in U-87 MG cells.
ED50 is ≤ 25.9 ng/ml, corresponding to a specific activity of 3.86 x 104 units/mg.
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SDS-PAGE analysis of ab288936.
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ESI TOF analysis of ab288936.
Predicted MW is 15569.82 Da (+/- 10 Da by ESI TOF). Observed MW is 15571.44 Da.
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HPLC analysis of ab288936.
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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Datasheet download
参考文献 (0)
ab283936 は論文での使用が確認できていません。