製品の詳細

  • 製品名

    Recombinant human IL-10 protein (Animal Free)
    IL-10 タンパク質・ペプチド 製品一覧
  • 生理活性

    Determined by the dose-dependent co-stimulation (with Human IL-4) of MC/9 cells.  The expected ED50 is ≤ 2.0 ng/ml, corresponding to a specific activity of ≥ 5 x 105 units/mg.

  • 精製度

    > 98 % SDS-PAGE.
    > 98% by HPLC analysis.
  • 発現系

    Escherichia coli
  • アクセッション番号

  • タンパク質長

    Full length protein
  • Animal free

    Yes
  • 由来

    Recombinant
    • 生物種

      Human
    • 配列

      MSPGQGTQSENSCTHFPGNLPNMLRDLRDAFSRVKTFFQMKDQLDNLLLK ESLLEDFKGYLGCQALSEMIQFYLEEVMPQAENQDPDIKAHVNSLGENLK TLRLRLRRCHRFLPCENKSKAVEQVKNAFNKLQEKGIYKAMSEFDIFINY IEAYMTMKIRN
    • 予測される分子量

      19 kDa
    • 領域

      19 to 178
    • 配列の追加情報

      This product is for the mature full length protein. The signal peptide is not included.

特性

Our Abpromise guarantee covers the use of ab217418 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    HPLC

    Functional Studies

    SDS-PAGE

  • 製品の状態

    Lyophilised
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • 再構成
    For lot specific reconstitution information please contact our Scientific Support Team.

関連情報

  • 別名

    • CSIF
    • Cytokine synthesis inhibitory factor
    • GVHDS
    • IL 10
    • IL-10
    • IL10
    • IL10_HUMAN
    • IL10A
    • Interleukin 10
    • Interleukin-10
    • MGC126450
    • MGC126451
    • T-cell growth inhibitory factor
    • TGIF
    see all
  • 機能

    Inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells.
  • 組織特異性

    Produced by a variety of cell lines, including T-cells, macrophages, mast cells and other cell types.
  • 配列類似性

    Belongs to the IL-10 family.
  • 細胞内局在

    Secreted.
  • Information by UniProt

参考文献

ab217418 has not yet been referenced specifically in any publications.

レビューと Q&A

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