Key features and details
- Expression system: Escherichia coli
- Purity: > 90% SDS-PAGE
- Active: Yes
- Suitable for: SDS-PAGE, WB, Functional Studies
製品名Recombinant human Hsp70 protein
Hsp70 タンパク質・ペプチド 製品一覧
精製度> 90 % SDS-PAGE.
Purified by Multi-step chromatography. > 90% pure as determined by SDS-PAGE and Western Blot analysis.
タンパク質長Full length protein
Our Abpromise guarantee covers the use of ab92415 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
備考Endotoxin level: < 50 EU/mg as determined by Limulus Amebocyte Lysate (LAL) gel clot assay.ATPase assay: positive
Concentration information loading...
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
Constituent: 2.68% PBS
This product is an active protein and may elicit a biological response in vivo, handle with caution.
- DnaK type molecular chaperone HSP70 1
- Epididymis secretory protein Li 103
関連性Function: In cooperation with other chaperones, the Hsp70 family stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. In case of rotavirus A infection, serves as a post-attachment receptor for the virus to facilitate entry into the cell. Tissue specificity: HSPA1B is testis-specific.
細胞内局在Cytoplasm. Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab92415 は 1 報の論文で使用されています。
- Tseng CC et al. GRP78 regulates CD44v membrane homeostasis and cell spreading in tamoxifen-resistant breast cancer. Life Sci Alliance 2:N/A (2019). PubMed: 31416894