Recombinant Human Glypican 3 protein (Tagged) (Biotin) (ab271530)
Key features and details
- Expression system: HEK 293 cells
- Purity: >= 71% SDS-PAGE
- Tags: His tag C-Terminus, Avi tag C-Terminus
- Suitable for: SDS-PAGE
製品の詳細
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製品名
Recombinant Human Glypican 3 protein (Tagged) (Biotin)
Glypican 3 タンパク質・ペプチド 製品一覧 -
精製度
>= 71 % SDS-PAGE. -
発現系
HEK 293 cells -
アクセッション番号
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タンパク質長
Protein fragment -
Animal free
No -
由来
Recombinant -
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生物種
Human -
配列
QPPPPPPDATCHQVRSFFQRLQPGLKWVPETPVPGSDLQVCLPKGPTCCS RKMEEKYQLTARLNMEQLLQSASMELKFLIIQNAAVFQEAFEIVVRHAKN YTNAMFKNNYPSLTPQAFEFVGEFFTDVSLYILGSDINVDDMVNELFDSL FPVIYTQLMNPGLPDSALDINECLRGARRDLKVFGNFPKLIMTQVSKSLQ VTRIFLQALNLGIEVINTTDHLKFSKDCGRMLTRMWYCSYCQGLMMVKPC GGYCNVVMQGCMAGVVEIDKYWREYILSLEELVNGMYRIYDMENVLLGLF STIHDSIQYVQKNAGKLTTTIGKLCAHSQQRQYRSAYYPEDLFIDKKVLK VAHVEHEETLSSRRRELIQKLKSFISFYSALPGYICSHSPVAENDTLCWN GQELVERYSQKAARNGMKNQFNLHELKMKGPEPVVSQIIDKLKHINQLLR TMSMPKGRVLDKNLDEEGFESGDCGDDEDECIGGSGDGMIKVKNQLRFLA ELAYDLDVDDAPGNSQQATPKDNEISTFHNLGNVH -
予測される分子量
63 kDa -
領域
25 to 559 -
タグ
His tag C-Terminus , Avi tag C-Terminus -
配列の追加情報
Includes alpha and beta subunits.
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標識
Biotin
関連製品
特性
Our Abpromise guarantee covers the use of ab271530 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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アプリケーション
SDS-PAGE
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製品の状態
Liquid -
備考
Enzymatically biotin-labeled using Avi-tag™ technology
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Concentration information loading...
前処理および保存
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保存方法および安定性
Shipped on Dry Ice. Store at -80°C. Avoid freeze / thaw cycle. Store In the Dark.
pH: 7.40
Constituents: 0.13% Sodium phosphate, 0.64% Sodium chloride, 0.02% Potassium chloride, 20% Glycerol (glycerin, glycerine)
関連情報
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別名
- DGSX
- Glypican proteoglycan 3
- Glypican-3 [Precursor]
see all -
機能
Cell surface proteoglycan that bears heparan sulfate. Inhibits the dipeptidyl peptidase activity of DPP4. May be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs. May play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function. May regulate growth and tumor predisposition. -
組織特異性
Highly expressed in lung, liver and kidney. -
関連疾患
Defects in GPC3 are the cause of Simpson-Golabi-Behmel syndrome type 1 (SGBS1) [MIM:312870]; also known as Simpson dysmorphia syndrome (SDYS). SGBS is a condition characterized by pre- and postnatal overgrowth (gigantism) with visceral and skeletal anomalies. -
配列類似性
Belongs to the glypican family. -
細胞内局在
Cell membrane and Secreted > extracellular space. - Information by UniProt
画像
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Western blot - Recombinant Human Glypican 3 protein (Tagged) (Biotin) (ab271530)
Recombinant Human Glypican 3 protein (Tagged) (Biotin) (ab271530) used as positive control in WB.
Lane 1: Non-reducing conditions.
Lane 2: Reducing conditions.
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SDS-PAGE - Recombinant Human Glypican 3 protein (Tagged) (Biotin) (ab271530)SDS-PAGE analysis of 7 µg ab271530.
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab271530 は論文での使用が確認できていません。