Bioactive grade

Recombinant human G-CSF protein (ab9692)

Submit a review Q&A (1)

製品の詳細

  • 製品名

    Recombinant human G-CSF protein
    G-CSF タンパク質・ペプチド 製品一覧

  • 生理活性

    The ED50, determined by the dose-dependent stimulation of the proliferation of murine NSF-60 cells, is < 0.1 ng/ml, corresponding to a specific activity of > 1 x 107 units/mg.

  • 精製度

    > 95 % SDS-PAGE.
    Sterile filtered Greater than 98% pure by SDS-PAGE and HPLC analyses.

  • エンドトキシン・レベル

    < 0.100 Eu/µg

  • 発現系

    Escherichia coli

  • タンパク質長

    Full length protein

  • Animal free

    No

  • 由来

    Recombinant

    • 生物種

      Human

    • 配列

      Human G-CSF is a 18.7 kDa protein containing 174 amino acid residues: TPLGPASSLP QSFLLKCLEQ VRKIQGDGAA LQEKLCATYK LCHPEELVLL GHSLG IPWAPLSSCPSQALQ LAGCLSQLHS GLFLYQGLLQ ALEGISPELG P TLDTLQLDV ADFATTIWQQMEELGMAPAL QPTQGAMPAF ASAFQRRA GG VLVASHLQSF LEVSYRVLRH LAQP

関連製品

特性

Our Abpromise guarantee covers the use of ab9692 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Functional Studies

    SDS-PAGE

  • 製品の状態

    Lyophilized

  • 備考

    The ED50 as determined by the dose-dependent stimulation of the proliferation of murine NFS-60 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg.

  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    n/a

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • 再構成
    For lot specific reconstitution information please contact our Scientific Support Team.

関連情報

  • 別名

    • C17orf33
    • Colony stimulating factor 3
    • Colony stimulating factor 3 (granulocyte)
    • CSF 3
    • CSF beta
    • CSF3
    • CSF3_HUMAN
    • CSF3OS
    • Csfg
    • Filgrastim
    • G-CSF
    • GCSA
    • GCSF
    • Granulocyte colony stimulating factor
    • Granulocyte colony-stimulating factor
    • Lenograstim
    • Macrophage granulocyte inducer 2
    • MGC45931
    • MGI 2
    • Pluripoietin
    see all

  • 機能

    Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes.

  • 配列類似性

    Belongs to the IL-6 superfamily.

  • 翻訳後修飾

    O-glycan consists of Gal-GalNAc disaccharide which can be modified with up to two sialic acid residues (done in recombinantly expressed G-CSF from CHO cells).

  • 細胞内局在

    Secreted.
  • Information by UniProt

プロトコール

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

参考文献 (0)

ab9692 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

ab9692 は論文での使用が確認できていません。

レビューと Q&A

Show All レビュー Q&A
レビューを送る 質問を送る

Question

I am interested in ordering recombinant human G-CSF from you. However,there are two products that describe the peptide as "Highly pure (>98%) recombinant hIL-11 (human Interleukin-11)". ab9752 has the recombinant murine sequence whereas ab9692 has the human sequence. Can I therefore assume that ab9692 is the human protein? Also, is IL-11 another name for G-CSF or simply an agonist of the G-CSF receptor?

Read More
Answer

Thank you for your email. There was a mistake on the datasheets for these proteins - ab9692 is recombinant human G-CSF and ab9752 is recombinant mouse G-CSF. They are not IL-ll proteins. I have updated the online datasheets to reflect this information. So, it sounds like what you want is ab9692, the recombinant human G-CSF. If you have any additional questions, please contact us again.

Read More

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com