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Recombinant Human DR1 protein (ab98246)

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SDS-PAGE - Recombinant Human DR1 protein (ab98246)

    Key features and details

    • Expression system: Escherichia coli
    • Purity: >= 85% SDS-PAGE
    • Tags: His tag N-Terminus
    • Suitable for: SDS-PAGE, MS

    製品の詳細

    • 製品名

      Recombinant Human DR1 protein

    • 精製度

      >= 85 % SDS-PAGE.
      ab98246 was purified using conventional chromatography.

    • 発現系

      Escherichia coli

    • アクセッション番号

      Q01658

    • タンパク質長

      Full length protein

    • Animal free

      No

    • 由来

      Recombinant

      • 生物種

        Human

      • 配列

        MGSSHHHHHHSSGLVPRGSHMASSSGNDDDLTIPRAAINKMIKETLPNVR VANDARELVVNCCTEFIHLISSEANEICNKSEKKTISPEHVIQALESLGF GSYISEVKEVLQECKTVALKRRKASSRLENLGIPEEELLRQQQELFAKAR QQQAELAQQEWLQMQQAAQQAQLAAASASASNQAGSSQDEEDDDDI

      • 予測される分子量

        22 kDa including tags

      • 領域

        1 to 176

      • タグ

        His tag N-Terminus

    特性

    Our Abpromise guarantee covers the use of ab98246 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • アプリケーション

      SDS-PAGE

      Mass Spectrometry

    • 質量分析

      MALDI-TOF

    • 製品の状態

      Liquid
    • Concentration information loading...

    前処理および保存

    • 保存方法および安定性

      Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

      pH: 8.00
      Constituents: 0.00174% PMSF, 0.316% Tris HCl, 10% Glycerol (glycerin, glycerine), 0.58% Sodium chloride

    関連情報

    • 別名

      • Down regulator of transcription 1
      • Down regulator of transcription 1 TBP binding
      • Down-regulator of transcription 1
      • down-regulator of transcription 1, TBP-binding (negative cofactor 2)
      • DR 1
      • Dr1
      • Dr1 protein
      • NC 2
      • NC2
      • NC2 beta
      • NC2-beta
      • NC2B_HUMAN
      • Negative co factor 2
      • Negative cofactor 2
      • Negative cofactor 2 beta
      • Negative cofactor 2-beta
      • Protein Dr1
      • TATA binding protein associated phosphoprotein
      • TATA box/binding protein associated phosphoprotein DR1
      • TATA-binding protein-associated phosphoprotein
      see all

    • 機能

      The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4.

    • 配列類似性

      Belongs to the NC2 beta/DR1 family.
      Contains 1 histone-fold domain.

    • 翻訳後修飾

      Phosphorylation regulates its interaction with TBP. Not phosphorylated when bound to DRAP1.

    • 細胞内局在

      Nucleus.
    • Information by UniProt

    画像

    • SDS-PAGE - Recombinant Human DR1 protein (ab98246)
      SDS-PAGE - Recombinant Human DR1 protein (ab98246)
      15% SDS-PAGE analysis of 3µg ab98246

    プロトコール

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    参考文献 (0)

    ab98246 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

    ab98246 は論文での使用が確認できていません。

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