製品名Recombinant Human CDKN3 protein
CDKN3 タンパク質・ペプチド 製品一覧
タンパク質長Full length protein
由来Baculovirus infected Sf9 cells
Our Abpromise guarantee covers the use of ab71474 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
Constituents: 0.00174% PMSF, 0.00385% DTT, 0.79% Tris HCl, 25% Glycerol, 0.29% Sodium chloride
- Cdk associated protein phosphatase
- CDK2 associated dual specificity phosphatase
機能May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues. Dephosphorylates CDK2 at 'Thr-160' in a cyclin-dependent manner.
関連疾患Defects in CDKN3 are found in patients with hepatocellular carcinoma (HCC) [MIM:114550].
配列類似性Belongs to the protein-tyrosine phosphatase family.
細胞内局在Cytoplasm > perinuclear region.
- Information by UniProt
ab71474 has not yet been referenced specifically in any publications.