Recombinant Human Calcium channel L type DHPR alpha 2 subunit/CACNA2D1 protein (Tagged) (ab235738)
Key features and details
- Expression system: Escherichia coli
- Purity: > 90% SDS-PAGE
- Tags: His tag N-Terminus
- Suitable for: SDS-PAGE
製品の詳細
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製品名
Recombinant Human Calcium channel L type DHPR alpha 2 subunit/CACNA2D1 protein (Tagged) -
精製度
> 90 % SDS-PAGE. -
発現系
Escherichia coli -
アクセッション番号
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タンパク質長
Protein fragment -
Animal free
No -
由来
Recombinant -
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生物種
Human -
配列
QPKPIGVGIPTINLRKRRPNIQNPKSQEPVTLDFLDAELENDIKVEIRNK MIDGESGEKTFRTLVKSQDERYIDKGNRTYTWTPVNGTDYSLALVLPTYS FYYIKAKLEETITQARYSETLKPDNFEESGYTFIAPRDYCN -
予測される分子量
32 kDa including tags -
領域
528 to 668 -
タグ
His tag N-Terminus -
配列の追加情報
N-terminal 6xHis-SUMO-tag.
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関連製品
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Related Products
特性
Our Abpromise guarantee covers the use of ab235738 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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アプリケーション
SDS-PAGE
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製品の状態
Liquid -
備考
This product was previously labelled as Calcium channel L type DHPR alpha 2 subunit
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Concentration information loading...
前処理および保存
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保存方法および安定性
Shipped at 4°C. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 7.2
Constituents: Tris buffer, 50% Glycerol (glycerin, glycerine)
関連情報
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別名
- CA2D1_HUMAN
- CACN A2
- CACNA2
see all -
機能
The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel. Plays an important role in excitation-contraction coupling. -
組織特異性
Isoform 1 is expressed in skeletal muscle. Isoform 2 is expressed in the central nervous system. Isoform 2, isoform 4 and isoform 5 are expressed in neuroblastoma cells. Isoform 3, isoform 4 and isoform 5 are expressed in the aorta. -
配列類似性
Belongs to the calcium channel subunit alpha-2/delta family.
Contains 1 cache domain.
Contains 1 VWFA domain. -
ドメイン
The MIDAS-like motif in the VWFA domain binds divalent metal cations and is required to promote trafficking of the alpha-1 (CACNA1) subunit to the plasma membrane by an integrin-like switch. -
翻訳後修飾
Proteolytically processed into subunits alpha-2-1 and delta-1 that are disulfide-linked. -
細胞内局在
Membrane. - Information by UniProt
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab235738 は論文での使用が確認できていません。