Anti-RanBP1 抗体 (ab2937)

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Western blot - Anti-RanBP1 antibody (ab2937)

    Key features and details

    • Rabbit polyclonal to RanBP1
    • Suitable for: WB
    • Reacts with: Human
    • Isotype: IgG

    製品の概要

    • 製品名

      Anti-RanBP1 antibody
      RanBP1 一次抗体 製品一覧

    • 製品の詳細

      Rabbit polyclonal to RanBP1

    • 由来種

      Rabbit

    • アプリケーション

      適用あり: WBmore details

    • 種交差性

      交差種: Human
      交差が予測される動物種: Mouse, Cow

    • 免疫原

      Synthetic peptide corresponding to Human RanBP1 aa 1-18.
      Sequence:

      MAAAKDTHEDHDTSTENT


      (Peptide available as ab4938)
      Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI

    • ポジティブ･コントロール

      • HeLa cell lysate

    • 特記事項

      Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.

      Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.

      We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.

      In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.

      We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.

      Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.

      Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.

    製品の特性

    アプリケーション

    Our Abpromise guarantee covers the use of ab2937 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    アプリケーション Abreviews 特記事項
    WB Use a concentration of 1 µg/ml. Detects a band of approximately 30 kDa (predicted molecular weight: 24 kDa).

    ターゲット情報

    • 機能

      Inhibits GTP exchange on Ran. Forms a Ran-GTP-RANBP1 trimeric complex. Increase GTP hydrolysis induced by the Ran GTPase activating protein RANGAP1. May act in an intracellular signaling pathway which may control the progression through the cell cycle by regulating the transport of protein and nucleic acids across the nuclear membrane.

    • 配列類似性

      Belongs to the RANBP1 family.
      Contains 1 RanBD1 domain.
    • Information by UniProt

    • 参照データベース

      see all

    • 別名

      • HTF9A antibody
      • RAN binding protein 1 antibody
      • Ran specific GTPase activating protein antibody
      • Ran-binding protein 1 antibody
      • Ran-specific GTPase-activating protein antibody
      • RANBP1 antibody
      • RANG_HUMAN antibody
      see all

    画像

    • Western blot - Anti-RanBP1 antibody (ab2937)
      Western blot - Anti-RanBP1 antibody (ab2937)
      All lanes : Anti-RanBP1 antibody (ab2937) at 1/1000 dilution

      Lane 1 : HeLa cell lysate
      Lane 2 : Human brain tissue lysate
      Lane 3 : NIH-3T3 cell lysate

      Lysates/proteins at 25 µg per lane.

      Secondary
      All lanes : HRP conjugated anti-rabbit

      Developed using the ECL technique.

      Predicted band size: 24 kDa
      Observed band size: 27 kDa
      why is the actual band size different from the predicted?


      Exposure time: 1 minute

    参考文献 (3)

    ab2937 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

    ab2937 は 3 報の論文で使用されています。

    • Prpar Mihevc S  et al. TDP-43 aggregation mirrors TDP-43 knockdown, affecting the expression levels of a common set of proteins. Sci Rep 6:33996 (2016). WB, ICC/IF . PubMed: 27665936
    • Štalekar M  et al. Proteomic analyses reveal that loss of TDP-43 affects RNA processing and intracellular transport. Neuroscience 293:157-70 (2015). WB, ICC/IF . PubMed: 25743254
    • Schulz M  et al. Proteomic analysis of peripheral blood mononuclear cells: selective protein processing observed in patients with rheumatoid arthritis. J Proteome Res 6:3752-9 (2007). WB ; Human . PubMed: 17705417

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