Anti-RAB27B 抗体 (ab76779)
Key features and details
- Mouse polyclonal to RAB27B
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-RAB27B antibody
RAB27B 一次抗体 製品一覧 -
製品の詳細
Mouse polyclonal to RAB27B -
由来種
Mouse -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human -
免疫原
Recombinant full length protein within Human RAB27B. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.
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ポジティブ・コントロール
- RAB27B transfected 293T cell lysate
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 7.40
Constituent: 100% PBS -
Concentration information loading...
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精製度
Protein A purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab76779の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB | (1) |
1/500 - 1/1000. Detects a band of approximately 25 kDa (predicted molecular weight: 25 kDa).
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特記事項 |
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WB
1/500 - 1/1000. Detects a band of approximately 25 kDa (predicted molecular weight: 25 kDa). |
ターゲット情報
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機能
May be involved in targeting uroplakins to urothelial apical membranes. -
組織特異性
Expressed primarily in testis. -
配列類似性
Belongs to the small GTPase superfamily. Rab family. -
細胞内局在
Membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 5874 Human
- Omim: 603869 Human
- SwissProt: O00194 Human
- Unigene: 25318 Human
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別名
- C25KG antibody
- Rab27b antibody
- RAB27B member RAS oncogene family antibody
see all
画像
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All lanes : Anti-RAB27B antibody (ab76779) at 1/500 dilution
Lane 1 : RAB27B transfected 293T cell lysate
Lane 2 : Non-transfected 293T cell lysate
Lysates/proteins at 25 µg per lane.
Secondary
All lanes : Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/5000 dilution
Developed using the ECL technique.
Predicted band size: 25 kDa
Observed band size: 25 kDa
データシートおよび資料
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Datasheet download
参考文献 (5)
ab76779 は 5 報の論文で使用されています。
- Park SS et al. Temsirolimus Enhances Anti-Cancer Immunity by Inducing Autophagy-Mediated Degradation of the Secretion of Small Extracellular Vesicle PD-L1. Cancers (Basel) 14:N/A (2022). PubMed: 36077620
- Zhou H et al. Therapeutic inhibition of GAS6-AS1/YBX1/MYC axis suppresses cell propagation and disease progression of acute myeloid leukemia. J Exp Clin Cancer Res 40:353 (2021). PubMed: 34753494
- Underwood R et al. The GTPase Rab27b regulates the release, autophagic clearance, and toxicity of a-synuclein. J Biol Chem 295:8005-8016 (2020). PubMed: 32350025
- Stephens DC et al. Spatiotemporal organization and protein dynamics involved in regulated exocytosis of MMP-9 in breast cancer cells. J Gen Physiol 151:1386-1403 (2019). PubMed: 31676484
- McGrath JA et al. Germline Mutation in EXPH5 Implicates the Rab27B Effector Protein Slac2-b in Inherited Skin Fragility. Am J Hum Genet 91:1115-21 (2012). PubMed: 23176819