Anti-Rab11A 抗体 (ab2921)
Key features and details
- Goat polyclonal to Rab11A
- Suitable for: WB
- Reacts with: Mouse
- Isotype: IgG
リコンビナント抗体で、ロット間での高い再現性を実現
- 異なるロット間での安定した再現性
- 容易なスケールアップ
- 評価試験による特異性の確認済み
- 倫理基準に準拠 - アニマル・フリーの生産
製品の概要
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製品名
Anti-Rab11A antibody
Rab11A 一次抗体 製品一覧 -
製品の詳細
Goat polyclonal to Rab11A -
由来種
Goat -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Mouse
交差が予測される動物種: Human -
免疫原
Synthetic peptide within Human Rab11A aa 204-216 (C terminal). The exact sequence is proprietary.
Sequence:TENKPKVQCCQNI
Database link: P62491 -
ポジティブ・コントロール
- WB: Mouse Heart lysate
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特記事項
Principal Names – RAB11A; YL8; RAB11A, member RAS oncogene family; RAB 11A, member oncogene family Official Gene Symbol - RAB11A GenBank Accession Number – NP_004654 LocusLink ID - 55072 (human) Gene Ontology terms - RAB small monomeric GTPaseThe Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 0.5% Tris, 0.5% BSA -
Concentration information loading...
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精製度
Immunogen affinity purified -
特記事項(精製)
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab2921の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 26 kDa (predicted molecular weight: 24 kDa).
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特記事項 |
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WB
Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 26 kDa (predicted molecular weight: 24 kDa). |
ターゲット情報
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機能
Regulates endocytic recycling. May exert its functions by interacting with multiple effector proteins in different complexes. Acts as a major regulator of membrane delivery during cytokinesis. Together with MYO5B and RAB8A participates in epithelial cell polarization. Together with RAB3IP, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis (By similarity). Together with MYO5B participates in CFTR trafficking to the plasma membrane and TF (Transferrin) recycling in nonpolarized cells. Required in a complex with MYO5B and RAB11FIP2 for the transport of NPC1L1 to the plasma membrane. Participates in the sorting and basolateral transport of CDH1 from the Golgi apparatus to the plasma membrane. Regulates the recycling of FCGRT (receptor of Fc region of monomeric Ig G) to basolateral membranes. -
配列類似性
Belongs to the small GTPase superfamily. Rab family. -
細胞内局在
Cell membrane. Recycling endosome membrane. Cleavage furrow. Translocates with RAB11FIP2 from the vesicles of the endocytic recycling compartment (ERC) to the plasma membrane. Localizes to the cleavage furrow. Colocalizes with PARD3, PRKCI, EXOC5, OCLN, PODXL and RAB8A in apical membrane initiation sites (AMIS) during the generation of apical surface and luminogenesis. - Information by UniProt
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参照データベース
- Entrez Gene: 8766 Human
- Entrez Gene: 53869 Mouse
- Omim: 605570 Human
- SwissProt: P62491 Human
- SwissProt: P62492 Mouse
- Unigene: 321541 Human
- Unigene: 1387 Mouse
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別名
- MGC1490 antibody
- Rab 11 antibody
- Rab 11A antibody
see all
画像
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Anti-Rab11A antibody (ab2921) at 2 µg/ml + Mouse heart tissue lysate (RIPA buffer) at 30 µg
Predicted band size: 24 kDa
Observed band size: 26 kDa why is the actual band size different from the predicted?Primary incubated for 1 hour. Detected by Western blot using chemiluminescence.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (1)
ab2921 は 1 報の論文で使用されています。
- Wrenn SM et al. Avian lungs: A novel scaffold for lung bioengineering. PLoS One 13:e0198956 (2018). PubMed: 29949597
レビューと Q&A
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