Anti-Rab11 抗体 (ab3612)
Key features and details
- Rabbit polyclonal to Rab11
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-Rab11 antibody
Rab11 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to Rab11 -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Rat, Rabbit, Chicken, Cow, Pig, Non human primates -
免疫原
Synthetic peptide corresponding to Human Rab11 aa 1-17.
Sequence:MGTRDDEYDYLFKVVLIC
(Peptide available asab41779) -
特記事項
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle. -
バッファー
Preservative: 0.05% Sodium azide
Constituents: 99% PBS, 0.1% BSA -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
Our Abpromise guarantee covers the use of ab3612 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
アプリケーション | Abreviews | 特記事項 |
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WB | Use at an assay dependent concentration. Detects a band of approximately 22 kDa (predicted molecular weight: 24 kDa). By Western blot, this antibody detects an ~22 kDa protein representing Rab 11 in CV1, PC3, and HeLa cell extract. Another less prominent, unknown band is also detected by this antibody at ~35 kDa. |
ターゲット情報
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機能
GTPase that modulates endosomal trafficking. Acts as a major regulator of membrane delivery during cytokinesis. -
配列類似性
Belongs to the small GTPase superfamily. Rab family. -
細胞内局在
Cell membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 415544 Chicken
- Entrez Gene: 532723 Cow
- Entrez Gene: 9230 Human
- Entrez Gene: 19326 Mouse
- Entrez Gene: 595117 Pig
- Entrez Gene: 100009072 Rabbit
- Entrez Gene: 79434 Rat
- Omim: 604198 Human
see all -
別名
- GTP binding protein YPT3 antibody
- GTP-binding protein ypt3 antibody
- H-YPT3 antibody
see all
プロトコール
参考文献 (24)
ab3612 は 24 報の論文で使用されています。
- Ma W et al. The Vacuolar Pathway of Long Peptide Cross-Presentation Can Be TAP Dependent. J Immunol 202:451-459 (2019). PubMed: 30559321
- Koumangoye R et al. A dileucine motif in the COOH-terminal domain of NKCC1 targets the cotransporter to the plasma membrane. Am J Physiol Cell Physiol 316:C545-C558 (2019). PubMed: 30865516
- Connor-Robson N et al. An integrated transcriptomics and proteomics analysis reveals functional endocytic dysregulation caused by mutations in LRRK2. Neurobiol Dis 127:512-526 (2019). PubMed: 30954703
- Parks XX et al. Fluvastatin inhibits Rab5-mediated IKs internalization caused by chronic Ca2+-dependent PKC activation. J Mol Cell Cardiol 129:314-325 (2019). PubMed: 30898664
- Markworth R et al. Sensory Axon Growth Requires Spatiotemporal Integration of CaSR and TrkB Signaling. J Neurosci 39:5842-5860 (2019). PubMed: 31123102