(R)-Tomoxetine hydrochloride, norepinephrine reuptake inhibitor (ab120758)

製品の概要

  • 製品名

    (R)-Tomoxetine hydrochloride, norepinephrine reuptake inhibitor
  • 製品の詳細

    Potent, selective norepinephrine reuptake inhibitor
  • 別名

    • Atomoxetine hydrochloride
  • 生理活性の詳細

    Potent and selective norepinephrine reuptake inhibitor. Ki values are 5, 77 and 1451 nM for inhibitors NET, DAT and SERT, respectively. Increases extraneuronal norepinephrine and dopamine levels within brain regions associated with Attention Deficit Hyperactivity Disorder.
  • 精製度

    > 99%
  • CAS 番号

    82248-59-7
  • 構造式

    Chemical Structure

製品の特性

参考文献

This product has been referenced in:

  • Swanson CJ  et al. Effect of the attention deficit/hyperactivity disorder drug atomoxetine on extracellular concentrations of norepinephrine and dopamine in several brain regions of the rat. Neuropharmacology 50:755-60 (2006). Read more (PubMed: 16427661) »
  • Bymaster FP  et al. Atomoxetine increases extracellular levels of norepinephrine and dopamine in prefrontal cortex of rat: a potential mechanism for efficacy in attention deficit/hyperactivity disorder. Neuropsychopharmacology 27:699-711 (2002). Read more (PubMed: 12431845) »

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