Puromycin dihydrochloride, Protein biosynthesis inhibitor (ab141453)
Key features and details
- Aminonuclease antibiotic agent. Protein biosynthesis inhibitor.
- CAS Number: 58-58-2
- Purity: > 98%
- Soluble in water to 75 mM
- Form / State: Solid
- Source: Synthetic
製品の概要
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製品名
Puromycin dihydrochloride, Protein biosynthesis inhibitor -
製品の詳細
Aminonuclease antibiotic agent. Protein biosynthesis inhibitor. -
精製度
> 98% -
特記事項
This product is manufactured by BioVision, an Abcam company and was previously called 1860 Puromycin Dihydrochloride. 1860-250 is the same size as the 250 mg size of ab141453.
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CAS 番号
58-58-2 -
構造式
製品の特性
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体系名
(2S)-2-Amino-N-[(2S,3S,4R,5R)-5-[6-(dimethylamino)purin-9-yl]-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]-3-(4-methoxyphenyl)propanamide dihydrochloride -
分子量
544.43 -
分子式
C22H29N7O5.2HCl -
PubChem 登録番号
443311 -
保存方法
Store at -20°C (desiccating conditions). -
溶解性
Soluble in water to 75 mM -
使用に関する注意
Refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES 線形表記
CN(C)C1=NC=NC2=C1N=CN2C3C(C(C(O3)CO)NC(=O)C(CC4=CC=C(C=C4)OC)N)O.Cl.Cl -
由来
Synthetic
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研究分野
画像
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (4)
ab141453 は 4 報の論文で使用されています。
- Xin M et al. Autophagy Inhibition Enhances the Anti-Tumor Activity of Methylseleninic Acid in Cisplatin-Resistance Human Lung Adenocarcinoma Cells. Front Pharmacol 13:890974 (2022). PubMed: 35592418
- Li C et al. PINK1-Dependent Mitophagy Reduced Endothelial Hyperpermeability and Cell Migration Capacity Under Simulated Microgravity. Front Cell Dev Biol 10:896014 (2022). PubMed: 35874841
- Hu J et al. Hexosamine biosynthetic pathway promotes the antiviral activity of SAMHD1 by enhancing O-GlcNAc transferase-mediated protein O-GlcNAcylation. Theranostics 11:805-823 (2021). PubMed: 33391506
- Gao Q et al. SLC27A5 deficiency activates NRF2/TXNRD1 pathway by increased lipid peroxidation in HCC. Cell Death Differ N/A:N/A (2019). PubMed: 31367013