Anti-PTGES2/Gbf1 抗体 (ab233274)
Key features and details
- Rabbit polyclonal to PTGES2/Gbf1
- Suitable for: WB, IHC-P
- Reacts with: Mouse, Human, Pig
- Isotype: IgG
製品の概要
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製品名
Anti-PTGES2/Gbf1 antibody
PTGES2/Gbf1 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to PTGES2/Gbf1 -
由来種
Rabbit -
アプリケーション
適用あり: WB, IHC-Pmore details -
種交差性
交差種: Mouse, Human, Pig
交差が予測される動物種: Cynomolgus monkey -
免疫原
Recombinant fragment (His-T7-tag) corresponding to Human PTGES2/Gbf1 aa 100 to the C-terminus. (Expressed in E.coli).
Database link: Q9H7Z7 -
ポジティブ・コントロール
- IHC-P: Human brain, liver, colorectal cancer and kidney tissues. WB: HepG2 and HeLa cell lysates; Pig and mouse heart lysates; Recombinant human PTGES2/Gbf1 protein.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
バッファー
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 44.12% PBS, 55.77% Glycerol (glycerin, glycerine) -
Concentration information loading...
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精製度
Immunogen affinity purified -
特記事項(精製)
ab233274 was purified by antigen-specific affinity chromatography followed by Protein A affinity chromatography. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab233274の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
Use a concentration of 0.2 - 2 µg/ml. Predicted molecular weight: 42 kDa.
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IHC-P |
Use a concentration of 5 - 20 µg/ml.
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特記事項 |
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WB
Use a concentration of 0.2 - 2 µg/ml. Predicted molecular weight: 42 kDa. |
IHC-P
Use a concentration of 5 - 20 µg/ml. |
ターゲット情報
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機能
Isomerase that catalyzes the conversion of unstable intermediate of prostaglandin E2 H2 (PGH2) into the more stable prostaglandin E2 (PGE2) form. May also have transactivation activity toward IFN-gamma (IFNG), possibly via an interaction with CEBPB; however, the relevance of transcription activation activity remains unclear. -
組織特異性
Widely expressed. Expressed in the heart, including apex, inter-ventricular septum, both atria and ventricles, but not in the aorta. Also expressed in fetal heart. Detected in various regions of the brain: cerebellum; occipital, frontal and parietal lobes. Also expressed in the lymph nodes, skeletal muscle, kidney and trachea, but not in the thymus or lung. Overexpressed in colorectal cancer. -
パスウェイ
Lipid metabolism; prostaglandin biosynthesis. -
配列類似性
Belongs to the GST superfamily.
Contains 1 glutaredoxin domain.
Contains 1 GST C-terminal domain. -
細胞内局在
Golgi apparatus membrane and Cytoplasm > perinuclear region. Synthetized as a Golgi membrane-bound protein, which is further cleaved into the predominant soluble truncated form. The truncated form is cytoplasmic and is enriched in the perinuclear region. - Information by UniProt
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参照データベース
- Entrez Gene: 102140040 Cynomolgus monkey
- Entrez Gene: 80142 Human
- Entrez Gene: 96979 Mouse
- Entrez Gene: 100155133 Pig
- Omim: 608152 Human
- SwissProt: Q9N0A4 Cynomolgus monkey
- SwissProt: Q9H7Z7 Human
- SwissProt: Q8BWM0 Mouse
see all -
別名
- C9orf15 antibody
- FLJ14038 antibody
- Gamma interferon activated transcriptional element binding factor 1 antibody
see all
画像
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Paraffin-embedded human brain tissue stained for PTGES2/Gbf1 using ab233274 at 10 µg/ml in immunohistochemical analysis. DAB staining.
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Paraffin-embedded human liver tissue stained for PTGES2/Gbf1 using ab233274 at 20 µg/ml in immunohistochemical analysis. DAB staining.
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Paraffin-embedded human colorectal cancer tissue stained for PTGES2/Gbf1 using ab233274 at 20 µg/ml in immunohistochemical analysis. DAB staining.
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Anti-PTGES2/Gbf1 antibody (ab233274) at 2 µg/ml + Recombinant human PTGES2/Gbf1 protein
Predicted band size: 42 kDa -
Anti-PTGES2/Gbf1 antibody (ab233274) at 2 µg/ml + HepG2 (human liver hepatocellular carcinoma cell line) cell lysate
Predicted band size: 42 kDa -
Anti-PTGES2/Gbf1 antibody (ab233274) at 2 µg/ml + Pig heart lysate
Predicted band size: 42 kDa -
Anti-PTGES2/Gbf1 antibody (ab233274) at 2 µg/ml + Mouse heart lysate
Predicted band size: 42 kDa -
Anti-PTGES2/Gbf1 antibody (ab233274) at 2 µg/ml + HeLa (human epithelial cell line from cervix adenocarcinoma) cell lysate
Predicted band size: 42 kDa -
Formalin-fixed, paraffin-embedded human kidney tissue stained for PTGES2/Gbf1 using ab233274 at 20 µg/ml in immunohistochemical analysis. DAB staining.
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (1)
ab233274 は 1 報の論文で使用されています。
- Wang T et al. Integrated analysis of proteomics and metabolomics reveals the potential sex determination mechanism in Odontobutis potamophila. J Proteomics 208:103482 (2019). PubMed: 31401171