Anti-PSME1 抗体 (ab3333)

Submit a review Q&A (1)References (3)

Key features and details

  • Rabbit polyclonal to PSME1
  • Suitable for: WB
  • Reacts with: Mouse, Rat, Hamster, Dog, Human
  • Isotype: IgG

製品の概要

  • 製品名

    Anti-PSME1 antibody
    PSME1 一次抗体 製品一覧

  • 製品の詳細

    Rabbit polyclonal to PSME1

  • 由来種

    Rabbit

  • 特異性

    Detects PSME1 (proteasome activator complex subunit 1).

  • アプリケーション

    適用あり: WBmore details

  • 種交差性

    交差種: Mouse, Rat, Hamster, Dog, Human
    交差が予測される動物種: Cow, Pig, Cynomolgus monkey

  • 免疫原

    Synthetic peptide corresponding to Human PSME1 aa 5-22.
    Sequence:

    RVQPEAQAKVDVFREDLC


    (Peptide available as ab4949)

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI

  • ポジティブ･コントロール

    • Rat brain extract.

  • 特記事項

    Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.

    Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.

    We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.

    In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.

    We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.

    Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.

    Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.

製品の特性

  • 製品の状態

    Liquid

  • 保存方法

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

  • バッファー

    Constituents: 0.1% BSA, 99% PBS
  • Concentration information loading...

  • 精製度

    Immunogen affinity purified

  • ポリ/モノ

    ポリクローナル

  • アイソタイプ

    IgG

  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab3333 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Detects a band of approximately 28 kDa (predicted molecular weight: 29 kDa).

By Western blot, this antibody detects a 28 kDa protein representing PSME1 in rat brain extract.

ターゲット情報

  • 機能

    Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome.

  • 配列類似性

    Belongs to the PA28 family.
  • Information by UniProt

  • 参照データベース

    see all

  • 別名

    • 11S regulator complex alpha subunit antibody
    • 11S regulator complex subunit alpha antibody
    • 29 kD MCP activator subunit antibody
    • 29kD MCP activator subunit antibody
    • Activator of multicatalytic protease subunit 1 antibody
    • IFI5111 antibody
    • IGUP I-5111 antibody
    • Interferon gamma IEF SSP 5111 antibody
    • Interferon gamma inducible protein 5111 antibody
    • Interferon gamma up regulated I 5111 protein antibody
    • Interferon gamma up-regulated I-5111 protein antibody
    • MGC8628 antibody
    • PA28a antibody
    • PA28alpha antibody
    • Proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) antibody
    • Proteasome activator 28 subunit alpha antibody
    • Proteasome activator complex subunit 1 antibody
    • Proteasome activator subunit 1 antibody
    • PSME1 antibody
    • PSME1_HUMAN antibody
    • REG-alpha antibody
    • REGalpha antibody
    see all

画像

  • Western blot - Anti-PSME1 antibody (ab3333)
    Western blot - Anti-PSME1 antibody (ab3333)

    Western blot detection of PSME1 in Hepa 1 cell lysate using ab3333.

参考文献 (3)

ab3333 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

ab3333 は 3 報の論文で使用されています。

  • Donnelly SK  et al. Rac3 regulates breast cancer invasion and metastasis by controlling adhesion and matrix degradation. J Cell Biol 216:4331-4349 (2017). PubMed: 29061650
  • Glogauer JE  et al. Neutrophils Increase Oral Squamous Cell Carcinoma Invasion through an Invadopodia-Dependent Pathway. Cancer Immunol Res 3:1218-26 (2015). PubMed: 26112922
  • Pla A  et al. TLR4 mediates the impairment of ubiquitin-proteasome and autophagy-lysosome pathways induced by ethanol treatment in brain. Cell Death Dis 5:e1066 (2014). WB ; Mouse . PubMed: 24556681

レビューと Q&A

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Question

I would like to confirm that ab3333will detect human reg 1 alpha by western blot. Also if not do you have an antibody that will? Thank-you Lisa

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Answer

Not to the best of my knoweldge. To eliminate all question, I would perform a BLAST search on the immunizing peptide.

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