Anti-PSME1 抗体 (ab3333)

Submit a review Q&A (1)References (3)
Western blot - Anti-PSME1 antibody (ab3333)

    Key features and details

    • Rabbit polyclonal to PSME1
    • Suitable for: WB
    • Reacts with: Mouse
    • Isotype: IgG

    製品の概要

    • 製品名

      Anti-PSME1 antibody
      PSME1 一次抗体 製品一覧

    • 製品の詳細

      Rabbit polyclonal to PSME1

    • 由来種

      Rabbit

    • 特異性

      Detects PSME1 (proteasome activator complex subunit 1).

    • アプリケーション

      適用あり: WBmore details

    • 種交差性

      交差種: Mouse
      交差が予測される動物種: Cow, Pig, Cynomolgus monkey

    • 免疫原

      Synthetic peptide corresponding to Human PSME1 aa 5-22.
      Sequence:

      RVQPEAQAKVDVFREDLC


      (Peptide available as ab4949)
      Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI

    • ポジティブ･コントロール

      • Rat brain extract.

    • 特記事項

      The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

      If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

    製品の特性

    • 製品の状態

      Liquid

    • 保存方法

      Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    • バッファー

      Constituents: 0.1% BSA, 99% PBS
    • Concentration information loading...

    • 精製度

      Immunogen affinity purified

    • ポリ/モノ

      ポリクローナル

    • アイソタイプ

      IgG

    • 研究分野

    アプリケーション

    The Abpromise guarantee

    Abpromise保証は、 次のテスト済みアプリケーションにおけるab3333の使用に適用されます

    アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。

    アプリケーション Abreviews 特記事項
    WB
    Use a concentration of 1 µg/ml. Detects a band of approximately 28 kDa (predicted molecular weight: 29 kDa).

    By Western blot, this antibody detects a 28 kDa protein representing PSME1 in rat brain extract.
    特記事項
    WB
    Use a concentration of 1 µg/ml. Detects a band of approximately 28 kDa (predicted molecular weight: 29 kDa).

    By Western blot, this antibody detects a 28 kDa protein representing PSME1 in rat brain extract.

    ターゲット情報

    • 機能

      Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome.

    • 配列類似性

      Belongs to the PA28 family.
    • Information by UniProt

    • 参照データベース

      see all

    • 別名

      • 11S regulator complex alpha subunit antibody
      • 11S regulator complex subunit alpha antibody
      • 29 kD MCP activator subunit antibody
      • 29kD MCP activator subunit antibody
      • Activator of multicatalytic protease subunit 1 antibody
      • IFI5111 antibody
      • IGUP I-5111 antibody
      • Interferon gamma IEF SSP 5111 antibody
      • Interferon gamma inducible protein 5111 antibody
      • Interferon gamma up regulated I 5111 protein antibody
      • Interferon gamma up-regulated I-5111 protein antibody
      • MGC8628 antibody
      • PA28a antibody
      • PA28alpha antibody
      • Proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) antibody
      • Proteasome activator 28 subunit alpha antibody
      • Proteasome activator complex subunit 1 antibody
      • Proteasome activator subunit 1 antibody
      • PSME1 antibody
      • PSME1_HUMAN antibody
      • REG-alpha antibody
      • REGalpha antibody
      see all

    画像

    • Western blot - Anti-PSME1 antibody (ab3333)
      Western blot - Anti-PSME1 antibody (ab3333)

      Western blot detection of PSME1 in Hepa 1 cell lysate using ab3333.

    参考文献 (3)

    ab3333 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

    ab3333 は 3 報の論文で使用されています。

    • Donnelly SK  et al. Rac3 regulates breast cancer invasion and metastasis by controlling adhesion and matrix degradation. J Cell Biol 216:4331-4349 (2017). PubMed: 29061650
    • Glogauer JE  et al. Neutrophils Increase Oral Squamous Cell Carcinoma Invasion through an Invadopodia-Dependent Pathway. Cancer Immunol Res 3:1218-26 (2015). PubMed: 26112922
    • Pla A  et al. TLR4 mediates the impairment of ubiquitin-proteasome and autophagy-lysosome pathways induced by ethanol treatment in brain. Cell Death Dis 5:e1066 (2014). WB ; Mouse . PubMed: 24556681

    レビューと Q&A

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    レビューを送る 質問を送る

    Question

    I would like to confirm that ab3333will detect human reg 1 alpha by western blot. Also if not do you have an antibody that will? Thank-you Lisa

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    Answer

    Not to the best of my knoweldge. To eliminate all question, I would perform a BLAST search on the immunizing peptide.

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