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製品名Psalmotoxin-1, ASIC1a blocker
製品の詳細Potent, selective ASIC1a blocker
配列EDCIPKWKGCVNRHGDCCEGLECWKRRRSFEVCVPKTPKT (Modifications: Disulfide bonds: 3-18, 10-23, 17-33)
保存方法Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
溶解性Soluble in water
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
This product has been referenced in:
- Mazzuca M et al. A tarantula peptide against pain via ASIC1a channels and opioid mechanisms. Nat Neurosci 10:943-5 (2007). Read more (PubMed: 17632507) »
- Salinas M et al. The receptor site of the spider toxin PcTx1 on the proton-gated cation channel ASIC1a. J Physiol 570:339-54 (2006). Read more (PubMed: 16284080) »
- Escoubas P et al. Recombinant production and solution structure of PcTx1, the specific peptide inhibitor of ASIC1a proton-gated cation channels. Protein Sci 12:1332-43 (2003). Read more (PubMed: 12824480) »