Anti-Proteasome 19S S4/PSMC1 抗体 (ab3317)
Key features and details
- Rabbit polyclonal to Proteasome 19S S4/PSMC1
- Suitable for: WB
- Reacts with: Mouse, Human, Non human primates
- Isotype: IgG
製品の概要
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製品名
Anti-Proteasome 19S S4/PSMC1 antibody
Proteasome 19S S4/PSMC1 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to Proteasome 19S S4/PSMC1 -
由来種
Rabbit -
特異性
Detects proteasome 19S subunit S4. -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Mouse, Human, Non human primates -
免疫原
Other Immunogen Type corresponding to Proteasome 19S S4/PSMC1. Yeast proteasome 19S subunit S4.
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特記事項
This product was previously labelled as Proteasome 19S S4
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
Constituents: 0.1% BSA, 99% PBS -
Concentration information loading... -
精製度
IgG fraction -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
Our Abpromise guarantee covers the use of ab3317 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB | 1/1000. Detects a band of approximately 56 kDa (predicted molecular weight: 49 kDa). This antibody detects a 56 kDa protein representing proteasome 19S subunit S4 in HeLa cell lysate. This antibody detects, to a lesser extent, an ~35 kDa protein which could correspond to subunit degradation product. |
ターゲット情報
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機能
The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. -
配列類似性
Belongs to the AAA ATPase family. -
細胞内局在
Cytoplasm. Nucleus. - Information by UniProt
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参照データベース
- Entrez Gene: 5700 Human
- Entrez Gene: 19179 Mouse
- Omim: 602706 Human
- SwissProt: P62191 Human
- SwissProt: P62192 Mouse
- Unigene: 356654 Human
- Unigene: 157105 Mouse
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別名
- 26S protease regulatory subunit 4 antibody
- 26S proteasome AAA-ATPase subunit RPT2 antibody
- MGC24583 antibody
see all
画像
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Western blot - Anti-Proteasome 19S S4/PSMC1 antibody (ab3317)
Western blot of proteasome 19S subunit S4 on HeLa cell lysate using ab3317.
プロトコール
データシートおよび資料
参考文献 (4)
ab3317 は 4 報の論文で使用されています。
- Adelöf J et al. PA28aß overexpression enhances learning and memory of female mice without inducing 20S proteasome activity. BMC Neurosci 19:70 (2018). PubMed: 30400847
- Zhou X et al. HIV Replication in CD4+ T Lymphocytes in the Presence and Absence of Follicular Dendritic Cells: Inhibition of Replication Mediated by {alpha}-1-Antitrypsin through Altered I{kappa}B{alpha} Ubiquitination. J Immunol 186:3148-55 (2011). WB, IP . PubMed: 21263074
- Rousseau E et al. Misfolding of proteins with a polyglutamine expansion is facilitated by proteasomal chaperones. J Biol Chem 284:1917-29 (2009). WB, ICC/IF ; Human, Rat . PubMed: 18986984
- Sun X et al. Molecular characterization of tumour heterogeneity and malignant mesothelioma cell differentiation by gene profiling. J Pathol 207:91-101 (2005). PubMed: 16007577
