製品名Anti-Prostate Secretory Protein/PSP antibody [EPR7346]
Prostate Secretory Protein/PSP 一次抗体 製品一覧
製品の詳細Rabbit monoclonal [EPR7346] to Prostate Secretory Protein/PSP
アプリケーション適用あり: WB, IHC-Pmore details
適用なし: ICC/IF or IP
A synthetic peptide corresponding to residues in Human Prostate Secretory Protein/PSP. (P08118)
- human prostate cancer, human prostate tissue
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
保存方法Shipped at 4°C. Store at -20°C.
解離定数（KD 値）KD = 7.11 x 10 -10 M Learn more about KD
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol, 0.05% BSA, 50% Tissue culture supernatant
Concentration information loading...
精製度Tissue culture supernatant
Our Abpromise guarantee covers the use of ab133296 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/10000 - 1/50000. Detects a band of approximately 16 kDa (predicted molecular weight: 13 kDa).|
|IHC-P||1/250 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.|
組織特異性Strongly expressed in prostate, liver, kidney, breast and penis. Also expressed in pancreas, esophagus, stomach, deodenum, colon, trachea, lung, salivary glands and fallopian tube. PSP94 is expressed in lung and breast, whereas PSP57 is found in kidney and bladder.
関連疾患Defects in MSMB are the cause of susceptibility to prostate cancer hereditary type 13 (HPC13) [MIM:611928]. It is a condition associated with familial predisposition to cancer of the prostate. Most prostate cancers are adenocarcinomas that develop in the acini of the prostatic ducts. Other rare histopathologic types of prostate cancer that occur in approximately 5% of patients include small cell carcinoma, mucinous carcinoma, prostatic ductal carcinoma, transitional cell carcinoma, squamous cell carcinoma, basal cell carcinoma, adenoid cystic carcinoma (basaloid), signet-ring cell carcinoma and neuroendocrine carcinoma.
配列類似性Belongs to the beta-microseminoprotein family.
細胞内局在Secreted. Sperm surface.
- Information by UniProt
- Beta microseminoprotein [Precursor] antibody
- Beta-microseminoprotein antibody
- HPC 13 antibody
Immunohistochemical analysis of paraffin-embedded Human prostate tissue labelling Prostate Secretory Protein/PSP with 1/250 ab133296.
Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
All lanes : Anti-Prostate Secretory Protein/PSP antibody [EPR7346] (ab133296) at 1/10000 dilution
Lane 1 : Human prostate cancer lysate
Lane 2 : Human prostate lysate
Lysates/proteins at 10 µg per lane.
Predicted band size: 13 kDa
Observed band size: 16 kDa why is the actual band size different from the predicted?
Equilibrium disassociation constant (KD)
Learn more about KD
Click here to learn more about KD
ab133296 has not yet been referenced specifically in any publications.