製品の概要

  • 製品名

    Prostaglandin H2, prostanoid
  • 製品の詳細

    Major prostanoid; important precursor in eicosanoid synthesis
  • 別名

    • PGH2
  • 生理活性の詳細

    Major prostanoid; important precursor in eicosanoid synthesis. Formed following catalysis of arachidonic acid (AA) by COX and is subsequently converted by cell-specific synthases to form biologically active PGs and thromboxane.
  • 精製度

    > 95%
  • CAS 番号

    42935-17-1
  • 構造式

    Chemical Structure

製品の特性

  • 体系名

    (5Z,9α,11α,13E,15S)-9,11-Epidioxy-15-hydroxyprosta-5,13-dien-1-oic acid
  • 分子量

    352.47
  • 分子式

    C20H32O5
  • 保存方法

    Shipped on Dry Ice. Store at -80°C. Avoid freeze / thaw cycle.
  • 溶解性

    Supplied in acetone (100 µg/ml)
  • 使用に関する注意

    Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 6 months. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES 線形表記

    CCCCC[C@@H](O)/C=C/[C@H]1[C@@H]2OO[C@@H](C2)[C@H]1C/C=CCCCC(O)=O
  • 由来

    Synthetic

  • 研究分野

参考文献

This product has been referenced in:

  • Malhotra S  et al. COX inhibitors for airway inflammation. Expert Opin Ther Targets 16:195-207 (2012). Read more (PubMed: 22324934) »
  • Lin L  et al. Expression of prostaglandin H2-mediated mechanism of vascular contraction in hypertensive rats. Relation to lipoxygenase and prostacyclin synthase activities. Circ Res 74:197-205 (1994). Read more (PubMed: 8293559) »
  • Gorman RR  et al. Inhibition of basal and hormone-stimulated adenylate cyclase in adipocyte ghosts by the prostaglandin endoperoxide prostaglandin H2. J Biol Chem 250:6460-3 (1975). Read more (PubMed: 169245) »

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