AB246832

Picro-Sirius Red Solution

Name: Picro-Sirius Red Solution (ab246832) | Abcam
Brand: Abcam Limited
SKU: AB246832
Price: 14000 JPY
Availability: InStock

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(40 Publications)

Picro-Sirius Red (PSR) Solution (CAS:88-89-1)(ab246832) is suitable for histological visualization of muscle and collagen fibers, a major component of the extracellular matrix (ECM) in tissue sections in IHC. Suitable to quantify collagen content, fiber density, and organization.

- Used to differentiate collagens type I and type III fibers
- Suitable for light microscopy and polarized light microscopy
- Compatible with our Lab essentials imaging workflow offering
- Proven performance: cited in over 35 publications
- Larger volume format available upon request

2 Images

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Picro-Sirius Red Solution (AB246832)

IHC-P

Lab

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Picro-Sirius Red Solution (AB246832)

ab150681 (Picro Sirius Red stain) staining collagen (red), muscle fibres (yellow), cytoplasm (yellow) and red blood cells (yellow) in formalin fixed paraffin embedded normal human colon.

*Tissue obtained from the Human Research Tissue Bank, supported by the NIHR Cambridge Biomedical Research Centre.

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Picro-Sirius Red Solution (AB246832)

ab150681 Picro Sirius Red Stain Kit (Connective Tissue Stain) staining formalin-fixed-paraffin embedded human skeletal muscle.

Key facts

製品の状態

Liquid

form

バッファー組成

pH: 1 - 3 Constituents: 1.2% Picric Acid, 0.1% Direct Red 80

storage-buffer

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製品の詳細

Picro-Sirius Red Solution ab246832 is intended for use in the histological visualization of muscle and collagen fibers in tissue sections. The stain may be viewed using standard light microscopy or polarized light resulting in birefringence of collagen fibers. Please refer to ab150681 Picro Sirius Red Stain Kit (Connective Tissue Stain) for more information on this solution as it is a component of the kit.

Light Microscopy
Collagen: Red
Muscle Fibers: Yellow
Cytoplasm: Yellow
Polarized Light Microscopy
Collagen: Yellow-Orange and Green Birefringence

Control Tissues: Lung, Uterus, Muscle, Kidney

Procedure:
1. Deparaffinize sections if necessary and hydrate to distilled water.
2. Apply adequate Picro-Sirius Red Solution to completely cover tissue section and incubate for 60 minutes.
3. Rinse slide quickly in two changes of Acetic Acid Solution (0.5%).
4. Rinse slide using absolute alcohol.
5. Dehydrate in 2 changes of absolute alcohol, clear, and mount in synthetic resin.

Other products for staining tissue sections

Find more kits and reagents in the special stains guide, or products for antigen retrieval, blocking, signal amplification, visualization, counterstaining, and mounting in the IHC kits and reagents guide.

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出荷温度及び保存条件

出荷温度

Ambient - Can Ship with Ice

短期保存温度

Ambient

長期保存温度

Ambient

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製品プロトコール

Visit the General protocols
Visit the Troubleshooting

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ターゲットの情報

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文献 (40)

Recent publications for all applications. Explore the full list and refine your search

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 58:e14402 PubMed40531753

2025

Protective effects of Aloe vera extract against doxorubicin-induced degeneration in ovarian follicles and stromal cells in mice.

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E I T de Assis,A N Godinho,J M O Freire,M F de Lima Neto,J J N Costa,A L P Souza,A P O do Monte,M H T Matos,A L M de Sousa,J R V Silva,A W B Silva

Reproduction (Cambridge, England) 169: PubMed40344189

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Reproductive seasonality influences follicle dynamics and the ovarian extracellular matrix structural properties in ewes.

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Johanne Grosbois,Vlastimil Srsen,Alba Muñoz Grande,Helen M Picton,Evelyn E Telfer

Redox biology 82:103554 PubMed40154102

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Redox regulation of lung endothelial PERK, unfolded protein response (UPR) and proliferation via NOX1: Targeted inhibition as a potential therapy for PAH.

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Genome biology 26:56 PubMed40087773

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A single-nucleus and spatial transcriptomic atlas of the COVID-19 liver reveals topological, functional, and regenerative organ disruption in patients.

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Scientific reports 15:8685 PubMed40082498

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Expression of tumor endothelial marker 1 in cardiac fibroblast contributes to atrial fibrosis in atrial fibrillation.

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Yi-Heng Li,Yu-Ning Hu,Ting-Chun Huang,Mu-Shiang Huang,Hsing-Chun Chung

Cell systems 16:101198 PubMed39970910

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Cold and hot fibrosis define clinically distinct cardiac pathologies.

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Shoval Miyara,Miri Adler,Kfir B Umansky,Daniel Häußler,Elad Bassat,Yalin Divinsky,Jacob Elkahal,David Kain,Daria Lendengolts,Ricardo O Ramirez Flores,Hanna Bueno-Levy,Ofra Golani,Tali Shalit,Michael Gershovits,Eviatar Weizman,Alexander Genzelinakh,Danielle M Kimchi,Avraham Shakked,Lingling Zhang,Jingkui Wang,Andrea Baehr,Zachary Petrover,Rachel Sarig,Tatjana Dorn,Alessandra Moretti,Julio Saez-Rodriguez,Christian Kupatt,Elly M Tanaka,Ruslan Medzhitov,Achim Krüger,Avi Mayo,Uri Alon,Eldad Tzahor

Cancer research communications 5:195-208 PubMed39785683

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Targeting Pancreatic Cancer Cell Stemness by Blocking Fibronectin-Binding Integrins on Cancer-Associated Fibroblasts.

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Chengsheng Wu,Tami Von Schalscha,Diva Sansanwal,Chen Qian,Qinlin Jiang,Ryan M Shepard,Hiromi I Wettersten,Stephen J McCormack,Sara M Weis,David A Cheresh

Advanced healthcare materials 13:e2401480 PubMed39388502

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Accelerating Oral Wound Healing Using Bilayer Biomaterial Delivery of FTY720 Immunotherapy.

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Afra I Toma,Daniel Shah,Daniela Roth,Jeremie Oliver Piña,Lauren Hymel,Thomas Turner,Archana Kamalakar,Ken Liu,Perry Bartsch,Leon Jacobs,Rena D'Souza,Dennis Liotta,Edward Botchwey,Nick J Willett,Steven L Goudy

Nature communications 15:8519 PubMed39353976

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CHIP ameliorates nonalcoholic fatty liver disease via promoting K63- and K27-linked STX17 ubiquitination to facilitate autophagosome-lysosome fusion.

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Nutrients 16: PubMed39125400

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Promoting Glutathione Synthesis: A Possibility for Treating Cardiomyopathy Induced by a Maternal Western Diet.

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Jialing Zhang,Jiayu Wang,Da Xu,Yiting Gui,Fan Bai,Yu Huo,Li Cao,Yonghao Gui

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Picro-Sirius Red Solution