STIM2 peptide (ab176417)
Key features and details
- Suitable for: Blocking
製品の詳細
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製品名
STIM2 peptide -
Animal free
No -
由来
Synthetic
関連製品
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Corresponding Antibody
特性
Our Abpromise guarantee covers the use of ab176417 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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アプリケーション
Blocking - Blocking peptide for Anti-STIM2 antibody (ab59342)
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製品の状態
Liquid -
Concentration information loading...
前処理および保存
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保存方法および安定性
Store at -20°C.
関連情報
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別名
- FLJ39527
- KIAA1482
- STIM 2
see all -
機能
Functions as a highly sensitive Ca(2+) sensor in the endoplasmic reticulum which activates both store-operated and store-independent Ca(2+)-influx. Regulates basal cytosolic and endoplasmic reticulum Ca(2+) concentrations. Upon mild variations of the endoplasmic reticulum Ca(2+) concentration, translocates from the endoplasmic reticulum to the plasma membrane where it probably activates the Ca(2+) release-activated Ca(2+) (CRAC) channels ORAI1, ORAI2 and ORAI3. May inhibit STIM1-mediated Ca(2+) influx. -
組織特異性
Expressed in all tissues and tumor cell lines examined. -
配列類似性
Contains 1 EF-hand domain.
Contains 1 SAM (sterile alpha motif) domain. -
翻訳後修飾
Glycosylated.
Phosphorylated predominantly on Ser residues. -
細胞内局在
Endoplasmic reticulum membrane. Dynamically translocates from a uniform endoplasmic reticulum distribution to punctual endoplasmic reticulum-plasma membrane junctions in response to decrease in endoplasmic reticulum Ca(2+) concentration. - Information by UniProt
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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Datasheet download
参考文献 (0)
ab176417 は論文での使用が確認できていません。
