Key features and details
- Purity: > 70% HPLC
- Suitable for: Blocking
Rhodopsin タンパク質・ペプチド 製品一覧
精製度> 70 % HPLC.
Peptides are analyzed by Reverse-Phase HPLC (RP-HPLC) in order to determine purity. Identities are confirmed by MALDI-MS.
Our Abpromise guarantee covers the use of ab4967 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and bovine rhodopsin, catalog ab3424. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~ 70-fold) for competitive inhibition of antibody-protein binding reactions.
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Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
再構成>95% pure, lyophilized synthetic peptide. Reconstitute with 0.1 ml of distilled water.
機能Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change leading to G-protein activation and release of all-trans retinal.
組織特異性Rod shaped photoreceptor cells which mediates vision in dim light.
関連疾患Retinitis pigmentosa 4
Night blindness, congenital stationary, autosomal dominant 1
配列類似性Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
翻訳後修飾Phosphorylated on some or all of the serine and threonine residues present in the C-terminal region.
Contains one covalently linked retinal chromophore.
細胞内局在Membrane. Synthesized in the inner segment (IS) of rod photoreceptor cells before vectorial transport to the rod outer segment (OS) photosensory cilia.
- Information by UniProt
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab4967 は 2 報の論文で使用されています。
- Spelat R et al. The dual action of glioma-derived exosomes on neuronal activity: synchronization and disruption of synchrony. Cell Death Dis 13:705 (2022). PubMed: 35963860
- Park YM et al. Acute estradiol treatment reduces skeletal muscle protein breakdown markers in early- but not late-postmenopausal women. Steroids 146:43-49 (2019). PubMed: 30928279