Recombinant mouse PDGFR alpha protein (ab60755)
Key features and details
- Expression system: Baculovirus infected Sf9 cells
- Purity: > 90% SDS-PAGE
- Active: Yes
- Tags: GST tag N-Terminus
- Suitable for: Functional Studies, SDS-PAGE
製品の詳細
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製品名
Recombinant mouse PDGFR alpha protein
PDGFR alpha タンパク質・ペプチド 製品一覧 -
生理活性
Specific activity: 14 nmol/min/mg.
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精製度
> 90 % SDS-PAGE.
Purity: >90% as determined by densitometry. Affinity purified. -
発現系
Baculovirus infected Sf9 cells -
アクセッション番号
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タンパク質長
Protein fragment -
Animal free
No -
由来
Recombinant -
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生物種
Mouse -
予測される分子量
100 kDa -
領域
550 to 1089 -
タグ
GST tag N-Terminus -
配列の追加情報
Recombinant fragment, corresponding to amino acids 550-end (cytoplasmic end) of Mouse PDGF Receptor alpha.
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関連製品
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Substrate reagent
特性
Our Abpromise guarantee covers the use of ab60755 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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アプリケーション
Functional Studies
SDS-PAGE
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製品の状態
Liquid -
備考
ab204877 (Poly (4:1 Glu, Tyr) peptide) can be utilized as a substrate for assessing kinase activity
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Concentration information loading...
前処理および保存
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保存方法および安定性
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 7.50
Constituents: 0.0038% EGTA, 0.00174% PMSF, 0.00385% DTT, 0.79% Tris HCl, 0.00292% EDTA, 25% Glycerol (glycerin, glycerine), 0.87% Sodium chlorideThis product is an active protein and may elicit a biological response in vivo, handle with caution.
関連情報
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別名
- Alpha-type platelet-derived growth factor receptor
- CD140 antigen-like family member A
- CD140a
see all -
機能
Receptor that binds both PDGFA and PDGFB and has a tyrosine-protein kinase activity. -
組織特異性
Expressed in primary and metastatic colon tumors and in normal colon tissue. Tumors may express a different isoform to that found in normal tissue. -
関連疾患
Note=A chromosomal aberration involving PDGFRA is found in some cases of hypereosinophilic syndrome. Interstitial chromosomal deletion del(4)(q12q12) causes the fusion of FIP1L1 and PDGFRA (FIP1L1-PDGFRA). -
配列類似性
Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
Contains 5 Ig-like C2-type (immunoglobulin-like) domains.
Contains 1 protein kinase domain. -
細胞内局在
Membrane. - Information by UniProt
画像
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Functional Studies - Recombinant mouse PDGFR alpha protein (ab60755)The specific activity of PDGFR alpha (ab60755) was determined to be 14 nmol/min/mg as per activity assay protocol
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SDS-PAGE - Recombinant mouse PDGFR alpha protein (ab60755)SDS PAGE analysis of ab60755 -
Functional Studies - Recombinant mouse PDGFR alpha protein (ab60755)Sample Kinase Activity Plot. -
SDS-PAGE - Recombinant mouse PDGFR alpha protein (ab60755)ab60755 on SDS-PAGE, MW ~100kDa.
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab60755 は論文での使用が確認できていません。