Recombinant Mouse DHODH protein (ab289736)
Key features and details
- Expression system: Cell free
- Purity: >= 85% SDS-PAGE
- Tags: His tag C-Terminus
- Suitable for: SDS-PAGE
製品の詳細
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製品名
Recombinant Mouse DHODH protein
DHODH タンパク質・ペプチド 製品一覧 -
精製度
>= 85 % SDS-PAGE. -
発現系
Cell free -
アクセッション番号
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タンパク質長
Full length protein -
Animal free
Yes -
由来
Recombinant -
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生物種
Mouse -
配列
LDAAIILGGG GLLFTSYLTA TGDDHFYAEY LMPALQRLLD PESAHRLAVR VISLGLLPRA TFQDSNMLEV RVLGHKFRNP VGIAAGFDKH GEAVDGLYKL GFGFVEVGSV TPQPQEGNPR PRVFRLPEDQ AVINRYGFNS HGLSAVEHRL RARQQKQTQL TTDGLPLGIN LGKNKTSVDA AADYVEGVRI LGPLADYLVV NVSSPNTAGL RSLQGKTELR RLLSKVLQER DALKGPQKPA VLVKIAPDLT AQDKEDIASV ARELGIDGLI ITNTTVSRPV GLQGALRSET GGLSGKPLRD LSTQTIREMY ALTQGTIPII GVGGVSSGQD ALEKIQAGAS LVQLYTALTF LGPPVVARVK RELEALLKER GFNTVTDAIG VDHRR -
予測される分子量
44 kDa including tags -
領域
11 to 395 -
タグ
His tag C-Terminus -
配列の追加情報
6xHis Full-length mature chain
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特性
Our Abpromise guarantee covers the use of ab289736 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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アプリケーション
SDS-PAGE
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製品の状態
Lyophilized -
Concentration information loading...
前処理および保存
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保存方法および安定性
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 7.40
Constituents: 0.87% Sodium chloride, 0.24% Tris, 0.05% dodecyl 2-(trimethylazaniumyl)ethyl phosphate, 6% Trehalose
関連情報
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別名
- DHOdehase
- Dhodh
- Dihydroorotate dehydrogenase
see all -
機能
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor. -
パスウェイ
Pyrimidine metabolism; UMP biosynthesis via de novo pathway; orotate from (S)-dihydroorotate (quinone route): step 1/1. -
関連疾患
Defects in DHODH are the cause of postaxial acrofacial dysostosis (POADS) [MIM:263750]; also known as Miller syndrome. POADS is characterized by severe micrognathia, cleft lip and/or palate, hypoplasia or aplasia of the posterior elements of the limbs, coloboma of the eyelids and supernumerary nipples. POADS is a very rare disorder: only 2 multiplex families, each consisting of 2 affected siblings born to unaffected, nonconsanguineous parents, have been described among a total of around 30 reported cases. -
配列類似性
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. -
翻訳後修飾
The uncleaved transit peptide is required for mitochondrial targeting and proper membrane integration. -
細胞内局在
Mitochondrion inner membrane. - Information by UniProt
画像
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SDS-PAGE - Recombinant Mouse DHODH protein (ab289736)SDS-PAGE analysis of ab289736
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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Datasheet download
参考文献 (0)
ab289736 は論文での使用が確認できていません。
