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AB165455

Recombinant Human ZNF358 protein (GST tag N-Terminus)

Recombinant Human ZNF358 protein (GST tag N-Terminus)

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Recombinant Human ZNF358 protein (GST tag N-Terminus) is a Human Full Length protein, in the 1 to 481 aa range, expressed in Wheat germ, suitable for ELISA, WB.

別名を表示する

Zinc finger protein 358, ZNF358

1 Images
SDS-PAGE - Recombinant Human ZNF358 protein (GST tag N-Terminus) (AB165455)
  • SDS-PAGE

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SDS-PAGE - Recombinant Human ZNF358 protein (GST tag N-Terminus) (AB165455)

ab165455 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Key facts

発現系

Wheat germ

タグ

GST tag N-Terminus

アプリケーション

WB, ELISA

applications

生物活性

No

アクセッション番号

Q9NW07

アニマルフリー

No

キャリアフリー

No

種

Human

バッファー組成

pH: 8 Constituents: 0.79% Tris HCl, 0.31% Glutathione

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "ELISA": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "WB": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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配列情報

[{"sequence":"MSSSFDLDPDVIGPVPLILDPNSDTLSPGDPKVDPISSGLTATPQVLATSPAVLPAPASPPRPFSCPDCGRAFRRSSGLSQHRRTHSGEKPYRCPDCGKSFSHGATLAQHRGIHTGARPYQCAACGKAFGWRSTLLKHRSSHSGEKPHHCPVCGKAFGHGSLLAQHLRTHGGPRPHKCPVCAKGFGQGSALLKHLRTHTGERPYPCPQCGKAFGQSSALLQHQRTHTAERPYRCPHCGKAFGQSSNLQHHLRIHTGERPYACPHCSKAFGQSSALLQHLHVHSGERPYRCQLCGKAFGQASSLTKHKRVHEGAAAAAAAAAAAAAAAAAGLGLGPGLSPASMMRPGQVSLLGPDAVSVLGSGLGLSPGTSSGRNPDPGSGPGTLPDPSSKPLPGSRSTPSPTPVESSDPKAGHDAGPDLVPSPDLDPVPSPDPDPVPSPDPNPVSCPDPCSPTRGTVSPALPTGESPEWVQEQGALLGPDG","proteinLength":"Full Length","predictedMolecularWeight":null,"actualMolecularWeight":null,"aminoAcidEnd":481,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Wheat germ","accessionNumber":"Q9NW07","tags":[{"tag":"GST","terminus":"N-Terminus"}]}]
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出荷温度及び保存条件

出荷温度
Dry Ice
短期保存温度
-80°C
長期保存温度
-80°C
分注に関する情報
Upon delivery aliquot
保管に関する情報
Avoid freeze / thaw cycle
False
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補足情報

This supplementary information is collated from multiple sources and compiled automatically.

ZNF358 also known as ZFP358 is a zinc finger protein playing a role in gene transcription regulation. It has a molecular mass of approximately 85 kDa. This protein is known to bind DNA in a sequence-specific manner using the zinc finger motifs to function as a transcription factor. ZNF358 expression occurs in multiple tissues with research indicating significant levels in the brain and heart. The protein's mechanical action involves modulating the transcription of specific genes impacting various biological processes.
Biological function summary

ZNF358 modulates critical processes in cellular differentiation and development. As a member of the transcription factor family ZNF358 does not form part of a known multi-protein complex. Instead it functions independently influencing the transcription of genes involved in cellular responses and structural development. This protein plays a role in maintaining cellular homeostasis affecting developmental stages by activating or repressing target gene transcription.

Pathways

ZNF358 influences several notably the Wnt signaling pathway and the Notch signaling pathway. In the Wnt signaling pathway ZNF358 interacts with proteins involved in cellular growth and differentiation such as β-catenin. This pathway plays a significant role in embryonic development and tissue regeneration. In relation to Notch signaling ZNF358 interacts with pathway components influencing cell fate determination and neural development collaborating with proteins like Notch receptors.

ZNF358 shows associations with developmental disorders particularly related to neural and cardiac malformations. Aberrant expression or dysfunction of ZNF358 may contribute to conditions like congenital heart defects due to its impact on cardiac development genes. Additionally disrupted ZNF358 function has links to neurodevelopmental disorders influencing neural pathway genes. Any interactions leading to disease often involve other transcription factors that interact with this protein in the developmental pathways.
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製品の性状

製品の状態

Liquid

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一般的な情報

機能

May be involved in transcriptional regulation.

配列の類似性

Belongs to the krueppel C2H2-type zinc-finger protein family.

細胞内局在性

Nucleus

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製品プロトコール

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ターゲットの情報

May be involved in transcriptional regulation.
See full target information ZNF358
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