Recombinant Human UPAR Protein (Active) (ab290079)
Key features and details
- Expression system: HEK 293 cells
- Purity: >= 95% HPLC
- Endotoxin level: <= 0.005 Eu/µg
- Active: Yes
製品の詳細
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製品名
Recombinant Human UPAR Protein (Active) -
生理活性
Loaded Human UPA/Urokinase, His Tag on Ni2+ Biosensor can bind Human UPAR with an affinity constant of 0.82 nM as determined in BLI assay (GatorBio Prime).
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精製度
>= 95 % HPLC. -
エンドトキシン・レベル
<=0.005 Eu/µg -
発現系
HEK 293 cells -
アクセッション番号
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タンパク質長
Protein fragment -
Animal free
Yes -
由来
Recombinant -
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生物種
Human -
配列
LRCMQCKTNGDCRVEECALGQDLCRTTIVRLWEEGEELELVEKSCTHSEK TNRTLSYRTGLKITSLTEVVCGLDLCNQGNSGRAVTYSRSRYLECISCGS SDMSCERGRHQSLQCRSPEEQCLDVVTHWIQEGEEGRPKDDRHLRGCGYL PGCPGSNGFHNNDTFHFLKCCNTTKCNEGPILELENLPQNGRQCYSCKGN STHGCSSEETFLIDCRGPMNQCLVATGTHEPKNQSYMVRGCATASMCQHA HLGDAFSMNHIDVSCCTKSGCNHPDLDVQYR -
領域
23 to 303 -
配列の追加情報
N-terminal glycine.
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特性
Our Abpromise guarantee covers the use of ab290079 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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製品の状態
Lyophilized -
Concentration information loading...
前処理および保存
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保存方法および安定性
Shipped at Room Temperature. Store at Room Temperature.
pH: 7.4
Constituents: 0.727% Dibasic monohydrogen potassium phosphate, 0.248% Monobasic dihydrogen potassium phosphate, 10.26% TrehaloseThis product is an active protein and may elicit a biological response in vivo, handle with caution.
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再構成Reconstitute with phosphate buffered saline. Store lyophilized form at room temperature. Reconstitute, aliquot and store at -80°C for 12 months or +4°C for 1week. Avoid repeated freeze-thaw. Lyophilized contents may appear as either a translucent film or a white power. This variance does not affect the quality of the product
関連情報
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別名
- CD 87
- CD87
- CD87 antigen
see all -
機能
Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form. -
組織特異性
Expressed in neurons of the rolandic area of the brain (at protein level). Expressed in the brain. -
配列類似性
Contains 3 UPAR/Ly6 domains. -
細胞内局在
Secreted and Cell membrane. - Information by UniProt
画像
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Biological Activity - Recombinant Human UPAR Protein (Active) (ab290079)
Loaded Human UPA/Urokinase, His Tag on Ni2+ Biosensor can bind Human UPAR with an affinity constant of 0.82 nM as determined in BLI assay (GatorBio Prime).
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SDS-PAGE - uPA Receptor/U-PAR protein (ab290079)SDS-PAGE analysis of ab290079 -
Mass Spectrometry - uPA Receptor/U-PAR protein (ab290079)Mass determination by ESI-TOF.
Predicted MW is 31373.15 Da. (+/- 10 Da by ESI-TOF). Observed MW is 31220.92 Da.
M -156 Da, due to Arginine truncation
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HPLC - uPA Receptor/U-PAR protein (ab290079)HPLC analysis of ab290079
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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Datasheet download
参考文献 (0)
ab290079 は論文での使用が確認できていません。
