Recombinant Human TRIB3 protein (ab186077)
Key features and details
- Expression system: Baculovirus infected Sf9 cells
- Purity: > 90% SDS-PAGE
- Tags: proprietary tag N-Terminus
- Suitable for: SDS-PAGE, WB
製品の詳細
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製品名
Recombinant Human TRIB3 protein
TRIB3 タンパク質・ペプチド 製品一覧 -
精製度
> 90 % SDS-PAGE.
Affinity purified. -
発現系
Baculovirus infected Sf9 cells -
アクセッション番号
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タンパク質長
Full length protein -
Animal free
No -
由来
Recombinant -
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生物種
Human -
配列
MRATPLAAPAGSLSRKKRLELDDNLDTERPVQKRARSGPQPRLPPCLLPL SPPTAPDRAT AVATASRLGPYVLLEPEEGGRAYQALHCPTGTEYTCKV YPVQEALAVLEPYARLPPHKHV ARPTEVLAGTQLLYAFFTRTHGDMHS LVRSRHRIPEPEAAVLFRQMATALAHCHQHGLVL RDLKLCRFVFADRE RKKLVLENLEDSCVLTGPDDSLWDKHACPAYVGPEILSSRASYSGK AA DVWSLGVALFTMLAGHYPFQDSEPVLLFGKIRRGAYALPAGLSAPARCLV RCLLRREP AERLTATGILLHPWLRQDPMPLAPTRSHLWEAAQVVPDGL GLDEAREEEGDREVVLYG -
予測される分子量
69 kDa including tags -
領域
1 to 358 -
タグ
proprietary tag N-Terminus
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関連製品
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Related Products
特性
Our Abpromise guarantee covers the use of ab186077 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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アプリケーション
SDS-PAGE
Western blot
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製品の状態
Liquid -
Concentration information loading...
前処理および保存
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保存方法および安定性
Shipped on Dry Ice. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.
pH: 7.50
Constituents: 0.79% Tris HCl, 0.003% EDTA, 0.004% DTT, 0.002% PMSF, 25% Glycerol (glycerin, glycerine), 0.88% Sodium chloride
関連情報
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別名
- C20orf97
- Neuronal cell death inducible putative kinase
- Neuronal cell death-inducible putative kinase
see all -
機能
Disrupts insulin signaling by binding directly to Akt kinases and blocking their activation. May bind directly to and mask the 'Thr-308' phosphorylation site in AKT1. Binds to ATF4 and inhibits its transcriptional activation activity. Interacts with the NF-kappa-B transactivator p65 RELA and inhibits its phosphorylation and thus its transcriptional activation activity. Interacts with MAPK kinases and regulates activation of MAP kinases. May play a role in programmed neuronal cell death but does not appear to affect non-neuronal cells. Does not display kinase activity. -
組織特異性
Highest expression in liver, pancreas, peripheral blood leukocytes and bone marrow. Also highly expressed in a number of primary lung, colon and breast tumors. Expressed in spleen, thymus, and prostate and is undetectable in other examined tissues, including testis, ovary, small intestine, colon, leukocyte, heart, brain, placenta, lung, skeletal muscle, and kidney. -
配列類似性
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. Tribbles subfamily.
Contains 1 protein kinase domain. -
細胞内局在
Nucleus. - Information by UniProt
画像
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SDS-PAGE - Recombinant Human TRIB3 protein (ab186077)
SDS-PAGE of ab186077.
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab186077 は論文での使用が確認できていません。