AB202190

Recombinant Human TNFSF18/GITRL protein (His tag C-Terminus)

Name: Recombinant Human TNFSF18/GITRL protein (ab202190) | Abcam
Brand: Abcam Limited
SKU: AB202190
Price: 123000 JPY
Availability: InStock

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Recombinant Human TNFSF18/GITRL protein (His tag C-Terminus) is a Human Fragment protein, in the 70 to 199 aa range, expressed in Escherichia coli, with >85%, suitable for SDS-PAGE.

別名を表示する

AITRL, GITRL, TL6, UNQ149/PRO175, TNFSF18, Tumor necrosis factor ligand superfamily member 18, Activation-inducible TNF-related ligand, Glucocorticoid-induced TNF-related ligand, hGITRL

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SDS-PAGE - Recombinant Human TNFSF18/GITRL protein (AB202190)

SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Human TNFSF18/GITRL protein (AB202190)

15% SDS-PAGE analysis of ab202190 (3 μg).

Key facts

精製度

>85% SDS-PAGE

発現系

Escherichia coli

アプリケーション

SDS-PAGE

applications

生物活性

アクセッション番号

Q9UNG2

アニマルフリー

キャリアフリー

種

Human

バッファー組成

pH: 8 Constituents: 10% Glycerol (glycerin, glycerine), 0.32% Tris HCl

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }

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配列情報

[{"sequence":"MQLETAKEPCMAKFGPLPSKWQMASSEPPCVNKVSDWKLEILQNGLYLIYGQVAPNANYNDVAPFEVRLYKNKDMIQTLTNKSKIQNVGGTYELHVGDTIDLIFNSEHQVLKNNTYWGIILIANPQEISLEHHHHHH","proteinLength":"Fragment","predictedMolecularWeight":"15.6 kDa","actualMolecularWeight":null,"aminoAcidEnd":199,"aminoAcidStart":70,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"Q9UNG2","tags":[{"tag":"His","terminus":"C-Terminus"}]}]

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出荷温度及び保存条件

出荷温度

Blue Ice

短期保存期間

1-2 weeks

短期保存温度

+4°C

長期保存温度

-20°C

分注に関する情報

Upon delivery aliquot

保管に関する情報

Avoid freeze / thaw cycle

False

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製品の性状

製品の状態

Liquid

補足情報

ab202190 was purified using conventional chromatography techniques.

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一般的な情報

機能

Cytokine that binds to TNFRSF18/AITR/GITR. Regulates T-cell responses. Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. Important for interactions between activated T-lymphocytes and endothelial cells. Mediates activation of NF-kappa-B. Triggers increased phosphorylation of STAT1 and up-regulates expression of VCAM1 and ICAM1 (PubMed : 23892569). Promotes leukocyte adhesion to endothelial cells (PubMed : 23892569). Regulates migration of monocytes from the splenic reservoir to sites of inflammation (By similarity).

配列の類似性

Belongs to the tumor necrosis factor family.

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製品プロトコール

Visit the General protocols
Visit the Troubleshooting

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ターゲットの情報

See full target information TNFSF18

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Abcam product promise

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Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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Recombinant Human TNFSF18/GITRL protein (His tag C-Terminus)