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Recombinant Human TLR7 protein (ab153341)

Submit a review Q&A (1)
SDS-PAGE - Recombinant Human TLR7 protein (ab153341)

    Key features and details

    • Expression system: Wheat germ
    • Purity: >= 80% Purified via GST Tag
    • Tags: GST tag N-Terminus
    • Suitable for: ELISA, WB

    製品の詳細

    • 製品名

      Recombinant Human TLR7 protein
      TLR7 タンパク質・ペプチド 製品一覧

    • 精製度

      >= 80 % Purified via GST Tag.
      Glutathione Sepharose

    • 発現系

      Wheat germ

    • アクセッション番号

      Q9NYK1

    • タンパク質長

      Protein fragment

    • Animal free

      No

    • 由来

      Recombinant

      • 生物種

        Human

      • 配列

        ARWFPKTLPCDVTLDVPKNHVIVDCTDKHLTEIPGGIPTNTTNLTLTINH IPDISPASFHRLDHLVEIDFRCNCVPIPLGSKNNMCIKRLQIKPRSFSGL

      • 予測される分子量

        37 kDa including tags

      • 領域

        27 to 126

      • タグ

        GST tag N-Terminus

    特性

    Our Abpromise guarantee covers the use of ab153341 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • アプリケーション

      ELISA

      Western blot

    • 製品の状態

      Liquid
    • Concentration information loading...

    前処理および保存

    • 保存方法および安定性

      Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

      pH: 8.00
      Constituents: 0.31% Glutathione, 0.79% Tris HCl

    関連情報

    • 別名

      • PRO285
      • TLR 7
      • Tlr7
      • TLR7_HUMAN
      • Toll like receptor 7
      • Toll-like receptor 7
      • UNQ248
      see all

    • 機能

      Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific of microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.

    • 組織特異性

      Detected in brain, placenta, spleen, stomach, small intestine, lung and in plasmacytoid pre-dendritic cells.

    • 配列類似性

      Belongs to the Toll-like receptor family.
      Contains 27 LRR (leucine-rich) repeats.
      Contains 1 TIR domain.

    • 細胞内局在

      Endoplasmic reticulum membrane. Endosome. Lysosome. Cytoplasmic vesicle > phagosome. Relocalizes from endoplasmic reticulum to endosome and lysosome upon stimulation with agonist.
    • Information by UniProt

    画像

    • SDS-PAGE - Recombinant Human TLR7 protein (ab153341)
      SDS-PAGE - Recombinant Human TLR7 protein (ab153341)
      ab153341 on a 12.5% SDS-PAGE stained with Coomassie Blue.

    プロトコール

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    参考文献 (0)

    ab153341 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

    ab153341 は論文での使用が確認できていません。

    レビューと Q&A

    Show All レビュー Q&A
    レビューを送る 質問を送る

    Question

    Is it possible for you to tell me the antibodies used to detect the proteins Human TLR7 protein fragment (ab153341) and Human TLR8 full length protein (ab153344) to generate the images displayed on your website?

    Read More
    Answer

    Thank you for contacting us.

    Actually, no antibody was used to create these images:

    As the purified, recombinant tagged fragments/proteins were used, the gels could directly be stained with Coomassie.

    Coomassie stains all proteins, hence the side bands. However, as the molecular weight of the sequence and the tag is known, there is no need for a more thorough staining process.


    I hope this information is helpful to you. Please do not hesitate to contact us if you need any more advice or information.

    -----------------------------------------------------------------------------------------------

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