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AB113141

Recombinant Human TFB1M protein (His tag N-Terminus)

Recombinant Human TFB1M protein (His tag N-Terminus)

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Recombinant Human TFB1M protein (His tag N-Terminus) is a Human Full Length protein, in the 28 to 346 aa range, expressed in Escherichia coli, with >90%, suitable for SDS-PAGE, FuncS.

別名を表示する

CGI-75, TFB1M, Mitochondrial 12S rRNA dimethylase 1, Mitochondrial transcription factor B1, h-mtTFB, h-mtTFB1, hTFB1M, mtTFB1

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SDS-PAGE - Recombinant Human TFB1M protein (His tag N-Terminus) (AB113141)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human TFB1M protein (His tag N-Terminus) (AB113141)

15% SDS-PAGE analysis of ab113141 (3μg)

Key facts

精製度

>90% SDS-PAGE

ab113141 was purified using conventional chromatography.

発現系

Escherichia coli

タグ

His tag N-Terminus

アプリケーション

SDS-PAGE, FuncS

applications

生物活性

No

アクセッション番号

Q8WVM0

アニマルフリー

No

キャリアフリー

No

種

Human

バッファー組成

pH: 8 Constituents: 20% Glycerol (glycerin, glycerine), 0.58% Sodium chloride, 0.32% Tris HCl, 0.02% (R*,R*)-1,4-Dimercaptobutan-2,3-diol

storage-buffer

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組合せ製品

Primary Antibodies

AB236901

Anti-TFB1M antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TFB1M antibody (AB236901)

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  • 0
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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "FuncS": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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配列情報

[{"linker":null,"sequence":"MGSSHHHHHHSSGLVPRGSHMQAAKQLSQNFLLDLRLTDKIVRKAGNLTNAYVYEVGPGPGGITRSILNADVAELLVVEKDTRFIPGLQMLSDAAPGKLRIVHGDVLTFKVEKAFSESLKRPWEDDPPNVHIIGNLPFSVSTPLIIKWLENISCRDGPFVYGRTQMTLTFQKEVAERLAANTGSKQRSRLSVMAQYLCNVRHIFTIPGQAFVPKPEVDVGVVHFTPLIQPKIEQPFKLVEKVVQNVFQFRRKYCHRGLRMLFPEAQRLESTGRLLELADIDPTLRPRQLSISHFKSLCDVYRKMCDEDPQLFAYNFREELKRRKSKNEEKEEDDAENYRL","proteinLength":"Full Length","predictedMolecularWeight":"38.8 kDa","actualMolecularWeight":null,"aminoAcidEnd":346,"aminoAcidStart":28,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"Q8WVM0","tags":[{"tag":"His","terminus":"N-Terminus"}]}]
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出荷温度及び保存条件

製品の状態
Liquid
出荷温度
Blue Ice
短期保存期間
1-2 weeks
短期保存温度
+4°C
長期保存温度
-20°C
分注に関する情報
Upon delivery aliquot
保管に関する情報
Avoid freeze / thaw cycle
False
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一般的な情報

機能

Mitochondrial methyltransferase which uses S-adenosyl methionine to dimethylate two highly conserved adjacent adenosine residues (A1583 and A1584) within the loop of helix 45 at the 3-prime end of 12S rRNA, thereby regulating the assembly or stability of the small subunit of the mitochondrial ribosome (PubMed : 12496758, PubMed : 25305075, PubMed : 31251801). Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity (PubMed : 11809803, PubMed : 12068295, PubMed : 12897151).

配列の類似性

Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. KsgA subfamily.

細胞内局在性

Mitochondrion

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製品プロトコール

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ターゲットの情報

Mitochondrial methyltransferase which uses S-adenosyl methionine to dimethylate two highly conserved adjacent adenosine residues (A1583 and A1584) within the loop of helix 45 at the 3-prime end of 12S rRNA, thereby regulating the assembly or stability of the small subunit of the mitochondrial ribosome (PubMed : 12496758, PubMed : 25305075, PubMed : 31251801). Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity (PubMed : 11809803, PubMed : 12068295, PubMed : 12897151).
See full target information TFB1M
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