AB156963

Recombinant Human SURF2 protein (His tag N-Terminus)

Name: Recombinant Human SURF2 protein (ab156963) | Abcam
Brand: Abcam Limited
SKU: AB156963
Price: 88000 JPY
Availability: InStock

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Recombinant Human SURF2 protein (His tag N-Terminus) is a Human Full Length protein, in the 1 to 256 aa range, expressed in Escherichia coli, with >90%, suitable for SDS-PAGE, Mass Spec.

別名を表示する

Surfeit locus protein 2, Surf-2, SURF2

1 Images

SDS-PAGE - Recombinant Human SURF2 protein (His tag N-Terminus) (AB156963)

SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human SURF2 protein (His tag N-Terminus) (AB156963)

15% SDS-PAGE analysis of ab156963 (3 µg).

Key facts

精製度

>90% SDS-PAGE

発現系

Escherichia coli

アプリケーション

SDS-PAGE, Mass Spec

applications

生物活性

アクセッション番号

Q15527

アニマルフリー

キャリアフリー

種

Human

バッファー組成

pH: 8 Constituents: 50% Glycerol (glycerin, glycerine), 1.17% Sodium chloride, 0.32% Tris HCl, 0.04% (R*,R*)-1,4-Dimercaptobutan-2,3-diol

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "Mass Spec": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }

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配列情報

[{"sequence":"MGSSHHHHHHSSGLVPRGSHMGSMSELPGDVRAFLREHPSLRLQTDARKVRCILTGHELPCRLPELQVYTRGKKYQRLVRASPAFDYAEFEPHIVPSTKNPHQLFCKLTLRHINKCPEHVLRHTQGRRYQRALCKYEECQKQGVEYVPACLVHRRRRREDQMDGDGPRPREAFWEPTSSDEGGAASDDSMTDLYPPELFTRKDLGSTEDGDGTDDFLTDKEDEKAKPPREKATDEGRRETTVYRGLVQKRGKKQLGSLKKKFKSHHRKPKSFSSCKQPG","proteinLength":"Full Length","predictedMolecularWeight":"32 kDa","actualMolecularWeight":null,"aminoAcidEnd":256,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"Q15527","tags":[{"tag":"His","terminus":"N-Terminus"}]}]

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出荷温度及び保存条件

出荷温度

Blue Ice

短期保存期間

1-2 weeks

短期保存温度

+4°C

長期保存温度

-20°C

分注に関する情報

Upon delivery aliquot

保管に関する情報

Avoid freeze / thaw cycle

False

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補足情報

This supplementary information is collated from multiple sources and compiled automatically.

SURF2 also known as Surfeit 2 is a protein with an approximate mass of 28 kDa. It is a component of the surfeit gene cluster which is compact and does not include any common regulatory elements shared by its member genes. SURF2 is expressed in various tissues but has significant expression in the lung and kidney. The protein itself functions as part of the cellular machinery specifically in membrane trafficking though detailed mechanisms at the molecular level require further study.

Biological function summary

This protein is engaged in critical cellular processes such as the modulation of intracellular trafficking. SURF2 is associated with the endoplasmic reticulum and Golgi apparatus hinting at a role in vesicle movement between these organelles. It works in conjunction with other proteins like CLIMP-63 and Ergic-53 participating in the correct sorting and dispatching of cargo proteins.

Pathways

SURF2 functions as a cog within the ER-Golgi transport pathway. It ensures effective vesicular trafficking which is essential for protein processing and secretion. Proteins such as Rab1 and Sec23 relate to SURF2 by collaborating in maintaining the integrity and functionality of this transport mechanism. These pathways are fundamental for cellular homeostasis and protein quality control.

SURF2 exhibits potential links to certain respiratory diseases due to its expression profile in lung tissue. Researchers hypothesize that improper function or expression of SURF2 could influence conditions like chronic obstructive pulmonary disease (COPD). Furthermore connections between SURF2 and other proteins like alpha-1-antitrypsin indicate a potential involvement in conditions where protease inhibitor imbalance plays a critical role. Understanding these associations might help develop therapeutic strategies targeting these pathways.

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製品の性状

製品の状態

Liquid

補足情報

ab156963 was purified using conventional chromatography techniques.

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一般的な情報

配列の類似性

Belongs to the SURF2 family.

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製品プロトコール

Visit the General protocols
Visit the Troubleshooting

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ターゲットの情報

See full target information SURF2

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Abcam product promise

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Recombinant Human SURF2 protein (His tag N-Terminus)